NCT02981901

Brief Summary

No structured organization for ovarian first line management emerges in France. Management across France seems to depend on regional contexts. Regions display no specific organization or delineate regional network for the ovarian cancer management or report centralized management revolving around referent centers. These different templates present a major problem in identifying differences, costs and benefit. To deal with this issue the Investigators propose a health economic evaluation based on cost-effectiveness analyses, completed with a budget impact analysis. This study will investigate the cost-effective management of patients with initial ovarian cancer using databases representative of different parts of French territories.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
376

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2017

Typical duration for all trials

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 28, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

December 5, 2016

Completed
27 days until next milestone

Study Start

First participant enrolled

January 1, 2017

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

August 23, 2018

Status Verified

August 1, 2018

Enrollment Period

2.9 years

First QC Date

November 28, 2016

Last Update Submit

August 22, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Incremental cost-effectiveness ratio expressed in cost per relapse-free year gained

    To perform a cost-effectiveness analysis in order to evaluate the most efficient organization for ovarian cancer in 1st line ot treatment

    2 years after diagnosis

Secondary Outcomes (3)

  • Incremental cost-effectiveness ratio expressed in cost per QALY(Quality-Adjusted Life Year) gained.

    2 years after diagnosis

  • Budget impact analysis

    2 years after diagnosis

  • Relapse-free survival (RFS)

    RFS will be assessed 2 years after diagnosis

Study Arms (1)

Patient with ovarian epithelial cancer

Ovarian epithelial cancer diagnosed in 2012

Other: Patient with ovarian epithelial cancer

Interventions

Patient with ovarian epithelial cancer

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Women with ovarian epithelial cancer diagnosed in 2012

You may qualify if:

  • Ovarian epithelial cancer initially diagnosed in 2012
  • Age \> 18 years old
  • Residency in France (Rhône-Alpes region, District of Calvados and Cotes d'Or)
  • First-line ovarian epithelial cancer

You may not qualify if:

  • Relapsed ovarian epithelial cancer
  • Non epithelial ovarian cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Calvados registry

Caen, France

Location

Côte d'or registry

Dijon, France

Location

Oveval

Lyon, France

Location

MeSH Terms

Conditions

Carcinoma, Ovarian Epithelial

Condition Hierarchy (Ancestors)

CarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsOvarian NeoplasmsEndocrine Gland NeoplasmsNeoplasms by SiteOvarian DiseasesAdnexal DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Neoplasms, FemaleUrogenital NeoplasmsGenital DiseasesEndocrine System DiseasesGonadal Disorders

Study Officials

  • Isabelle RAY-COQUARD, PU-PH

    Centre Leon Berard

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 28, 2016

First Posted

December 5, 2016

Study Start

January 1, 2017

Primary Completion

December 1, 2019

Study Completion

December 1, 2019

Last Updated

August 23, 2018

Record last verified: 2018-08

Locations