ARENA - Project Atrial Fibrilation Rhine-Neckar Region

NCT02978248 | Completed

• 1 other identifier: ARENA
• Study Type: observational
• Target: 2,777
• Locations: 1 country
• Sites: 1

Brief Summary

ARENA aims to inform patients about the symptoms and the risks of atrial fibrilation. The study design includes three study arms:

1. 1.ARENA Intervention: This project will examine the effectiveness of population education.
2. 2.ARENA Medication: The aim is to examine the patient's adherence and to analyze whether there are any complications.
3. 3.ARENA Migration: ARENA migration aims to examine whether a targeted population education can improve the care of people with a Turkish migration background.

Conditions

Atrial Fibrillation

Outcome Measures

Primary Outcomes (1)

• Number of Prevented strokes in participants

  10 years

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with atrial fibrilation in the Rhein-Neckar Region in Germany, recruted by their general practitioner or during a hospital stay.

You may qualify if:

• Willingness to participate
• Atiral fibrilation
• years or older

You may not qualify if:

• Not willing to participate

Sponsors & Collaborators

• Stiftung Institut fuer Herzinfarktforschung: lead

Study Sites (1)

Universitätsklinikum Heidelberg

Heidelberg, Baden-Wurttemberg, 69120, Germany

Location

Related Publications (3)

• Brockmuller C, Meid AD, Senges J, Hochadel M, Haefeli WE, Stoll F. Phenotypes of Patients with Direct Oral Anticoagulant (DOAC) Underdosing in Atrial Fibrillation: Results from the ARENA Registry. Clin Drug Investig. 2025 Jan;45(1):29-43. doi: 10.1007/s40261-024-01411-w. Epub 2024 Dec 12.

  PMID: 39666256 DERIVED

• Zylla MM, Ozdemir B, Hochadel M, Zeymer U, Akin I, Grau A, Schneider S, Alonso A, Waldecker B, Suselbeck T, Schwacke H, Haass M, Zahn R, Borggrefe M, Senges J, Frey N, Thomas D. Community-based analysis of stroke prevention and effect of public interventions in atrial fibrillation: results from the ARENA project. Clin Res Cardiol. 2025 Jan;114(1):138-149. doi: 10.1007/s00392-024-02510-6. Epub 2024 Aug 8.

  PMID: 39115608 DERIVED

• Sadlonova M, Salzmann S, Senges J, Celano CM, Huffman JC, Borggrefe M, Akin I, Thomas D, Schwarzbach CJ, Kleemann T, Schneider S, Hochadel M, Suselbeck T, Schwacke H, Alonso A, Haass M, Ladwig KH, Herrmann-Lingen C. Generalized anxiety is a predictor of impaired quality of life in patients with atrial fibrillation: Findings from the prospective observational ARENA study. J Psychosom Res. 2024 Jan;176:111542. doi: 10.1016/j.jpsychores.2023.111542. Epub 2023 Nov 8.

  PMID: 37977094 DERIVED

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Martin Borggrefe, Prof. Dr.

  Universitätsmedizin Mannheim

  PRINCIPAL INVESTIGATOR

• Walter E. Haefeli, Prof. Dr.

  University Hospital Heidelberg

  STUDY CHAIR

• Ömer Sanatci, Dr. med.

  Praxis Merz Sanatci

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 23, 2016
• First Posted: November 30, 2016
• Study Start: August 1, 2016
• Primary Completion: December 31, 2018
• Study Completion: July 19, 2021
• Last Updated: April 12, 2023

Record last verified: 2022-05

Data Sharing

• IPD Sharing: Will not share

Locations

DE (1)