NCT02972112

Brief Summary

Women in their 3rd trimester, represent a unique segment of the tokophobic population. In these cases help is needed within a very short and limited period of time. To date, no specific treatment targets this population in order to ameliorate the anxiety and to provide these women and their newborns with better obstetric and psychiatric outcomes. The present study investigates an accessible individual two session intervention conducted by midwives skilled in CBT (cognitive behavioral therapy) . This intervention is designed to enable stronger emotional regulation and increase of their capacity to accept unexpected changes during labor and feelings of control. The investigators expect this psychological adjustment to lead to a better course of delivery, less interventions including caesarian sections, and subjective birth experience.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 30, 2016

Completed
2 days until next milestone

Study Start

First participant enrolled

November 1, 2016

Completed
22 days until next milestone

First Posted

Study publicly available on registry

November 23, 2016

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2019

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2020

Completed
Last Updated

November 23, 2016

Status Verified

November 1, 2016

Enrollment Period

2.9 years

First QC Date

October 30, 2016

Last Update Submit

November 21, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pregnancy-Related Anxiety Questionnaire

    a widely used instrument to assess and identify pregnancy-specific anxiety in women

    In the end of second session of intervention- up to 4 weeks from screening

Study Arms (2)

Study group

ACTIVE COMPARATOR

will receive 2 sessions of 90 minutes each of a cognitive behavioral protocol for the treatment of Tokophobia administered by a CBT trained midwife.

Behavioral: CBT

Control group

SHAM COMPARATOR

will receive 2 sessions of a delivery preparation course (practice as usual).

Other: Sham

Interventions

CBTBEHAVIORAL

novel cognitive behavioral protocol for the treatment of tokophobia

Study group
ShamOTHER

standard birth preparation sessions.

Control group

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Hebrew speaking pregnant women week 32 + 0 to 37 + 0
  • fulfilling the criteria for a specific phobia diagnosed by SCID (Structured Clinical Interview for the Diagnostic) in accordance with DSM-V (Diagnostic and Statistical Manual) and the Fear of Vaginal Delivery Questionnaire (FDQ).

You may not qualify if:

  • Women who suffer from a psychotic disorder, PTSD or suicidal ideation
  • High risk pregnancies
  • Alcoholism or drug abuse and dependence.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Tel Aviv Sourasky Medical Center

Tel Aviv, Israel

Location

Related Publications (1)

  • O'Connell MA, Khashan AS, Leahy-Warren P, Stewart F, O'Neill SM. Interventions for fear of childbirth including tocophobia. Cochrane Database Syst Rev. 2021 Jul 7;7(7):CD013321. doi: 10.1002/14651858.CD013321.pub2.

MeSH Terms

Conditions

Phobia, Specific

Interventions

salicylhydroxamic acid

Central Study Contacts

Gabi Aisenberg Romano, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 30, 2016

First Posted

November 23, 2016

Study Start

November 1, 2016

Primary Completion

October 1, 2019

Study Completion

October 1, 2020

Last Updated

November 23, 2016

Record last verified: 2016-11

Locations