High Flow Nasal Cannulae Oxygen Therapy in Respiratory Insufficiency Patients

NCT02972021 | Unknown DMC

• 1 other identifier: shsk20160722
• Study Type: interventional
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic respiratory insufficiency in patients with advanced disease to the late treatment depends mainly on mechanical ventilation and other high intensity respiratory support therapy. Strengthen the stability of chronic respiratory insufficiency intervention can reduce the frequency and extent of acute disease, saving medical resources.High-flow nasal cannula (HFNC), as a new non-invasive oxygen therapy system, has gradually become a weapon of respiratory support therapy. There is little research on the role of HFNC in oxygen therapy for chronic respiratory insufficiency. Our previous studies have found the potential value of HFNC in chronic respiratory insufficiency. The aim of this project is to promote the use of HFNC in the t reatment of chronic respiratory insufficiency in HFRS in Shanghai first, second and third grade hospitals in an effort to confirm that HFNC can improve the prognosis of patients with chronic respiratory insufficiency compared with nasal oxygen therapy.

Conditions

Patients With Respiratory Insufficiency

Keywords

respiratory insufficiency; High-flow nasal cannula

Outcome Measures

Primary Outcomes (2)

• Improve dyspnea score

  up to 12 months after oxygen therapy

• Length of hospital stay

  up to 12 months after oxygen therapy

Study Arms (2)

control

OTHER

Pure oxygen by nasal cannula group

Device: High-flow nasal cannula

HFNC

EXPERIMENTAL

oxygen by High-flow nasal cannula

Device: High-flow nasal cannula

Interventions

High-flow nasal cannula DEVICE

HFNC; control

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \- Patients with chronic respiratory insufficiency who require long-term oxygen therapy.
• Age 18-85 years old. Agree to participate in this study.

You may not qualify if:

• \- Patients with advanced respiratory support (invasive mechanical ventilation, noninvasive mechanical ventilation) indications Cardiovascular disease caused by respiratory insufficiency Immune dysfunction caused by respiratory insufficiency Tumor-induced respiratory insufficiency People with disturbance of consciousness

Sponsors & Collaborators

• Shanghai 10th People's Hospital: lead

Study Sites (1)

Shanghai Tenth Hospital

Shanghai, Shanghai Municipality, 200072, China

Location

MeSH Terms

Conditions

Respiratory Insufficiency

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases

Central Study Contacts

HU PENG, MD

CONTACT

+821666304586; denkepeng@189.cn

YUANZHUO CHEN, MD

CONTACT

+821666304586; chenyuanzhuo021@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: department of emergency

Study Record Dates

• First Submitted: November 21, 2016
• First Posted: November 23, 2016
• Study Start: December 1, 2016
• Primary Completion: December 1, 2018
• Last Updated: November 23, 2016

Record last verified: 2016-11

Locations

CN (1)