Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)

NCT02970123 | Completed

• 2 other identifiers: IRB_000934771R21DK106574-01A1
• Study Type: interventional
• Target: 106
• Locations: 1 country
• Sites: 1

Brief Summary

Sedentary behavior is engaging in activities in the seated or lying position that barely raise the energy expenditure level and has emerged as an important risk factor for obesity, diabetes, cardiovascular disease and mortality. The primary hypothesis is that the Sit Less, Interact, Move More (SLIMM) intervention in Chronic Kidney Disease (CKD) will be effective in decreasing sedentary duration by increasing casual walking duration and thereby, increase physical activity energy expenditure.

Conditions

Chronic Kidney Disease

Outcome Measures

Primary Outcomes (2)

• Change in Sedentary Activity Duration

  Change in sedentary activity duration (average sedentary minutes per hour), as measured by a validated accelerometry monitor from baseline to 24 weeks

  Baseline and 24 Weeks

• Change in Casual Walking Duration

  Change in casual walking activity duration (average walking minutes per hour), as measured by a validated accelerometry monitor from baseline to 24 weeks

  Baseline and 24 Weeks

Secondary Outcomes (3)

• Change in Waist Circumference

  Baseline and 24 Weeks

• Change in Non-Exercise Activity Thermogenesis

  Baseline and 24 Weeks

• Change in Physical Function

  Baseline and 24 Weeks

Study Arms (2)

SLIMM Intervention

EXPERIMENTAL

Sit Less, Interact, Move More (SLIMM): instruction and monitoring feedback to promote decrease in sedentary activity duration, increase in casual walking duration, and increase in sedentary breaks

Behavioral: Sit Less, Interact, Move More (SLIMM)

Standard of Care

NO INTERVENTION

Subjects will receive standard of care treatment for chronic kidney disease, with no instruction or feedback to alter sedentary or casual walking durations

Interventions

Sit Less, Interact, Move More (SLIMM) BEHAVIORAL

SLIMM Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Stage 3/4 Chronic Kidney Disease, as defined by estimated glomerular filtration rate (eGFR) 15 to \< 60 ml/min/1.73m\^2
• Body Mass Index (BMI): 25 to 39.9 kg/m\^2
• Able to achieve gait speed of \> 1 m/sec and able to walk ≥ 320 meters in the 6-minute walk test

You may not qualify if:

• Previous renal replacement therapy
• Life expectancy \< 1 year
• Pregnancy
• Prison incarceration

Sponsors & Collaborators

• Srinvasan Beddhu: lead
• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): collaborator

Study Sites (1)

University of Utah

Salt Lake City, Utah, 84132, United States

Location

Related Publications (70)

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  PMID: 33888536 DERIVED

Related Links

• A 2-Minute Walk May Counter the Harms of Sitting: By Gretchen Reynolds
• . Walking 2 Minutes An Hour Boosts Health, But It's No Panacea. By Patti Neighmond
• The Department of Health. The Sedentary Behaviour and Obesity Expert Working Group: Sedentary Behaviour and Obesity: Review of the Current Scientific Evidence
• Centers for Disease Control and Prevenion. National Center for Health Statistics -NHANES 2003-2004
• Utah's Population: Growing fast, Concentrating more, Diversifying rapidly. Utah Legislature Briefing Paper

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Srinivasan Beddhu, M.D.

  University of Utah

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 17, 2016
• First Posted: November 21, 2016
• Study Start: December 1, 2016
• Primary Completion: September 12, 2019
• Study Completion: September 12, 2019
• Last Updated: September 17, 2019

Record last verified: 2019-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)