Hunger, Satiety, and Metabolic Responses to High-fat Meals of Varying Fatty Acid Composition
1 other identifier
interventional
16
1 country
1
Brief Summary
This study evaluates the effects of dietary fatty acid composition from high fat meals on markers of hunger, satiety and metabolism.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Oct 2016
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2016
CompletedFirst Submitted
Initial submission to the registry
November 8, 2016
CompletedFirst Posted
Study publicly available on registry
November 17, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2018
CompletedJuly 26, 2018
July 1, 2018
1.7 years
November 8, 2016
July 24, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Peptide-YY
18 months
Secondary Outcomes (1)
Visual Analog Scale
18 months
Study Arms (3)
MUFA-rich HF Meal
EXPERIMENTALHigh-fat meal rich in monounsaturated fatty acids
PUFA-rich HF Meal
EXPERIMENTALHigh-fat meal rich in polyunsaturated fatty acids
SFA-rich HF Meal
EXPERIMENTALHigh-fat meal rich in saturated fatty acids
Interventions
Eligibility Criteria
You may qualify if:
- BMI of \>18.5-24.9kg/m2
- Woman
- yrs of age
You may not qualify if:
- Evidence of weight loss or gain exceeding 5% of their body weight within the past 3 months.
- Plans to lose weight or begin a weight loss program between initiation of study and final testing.
- Plans to begin an exercise program or change current exercise routines between initiation of study and final testing.
- Is on a medically prescribed diet
- Does not consume breakfast regularly
- Rate less than 80% of foods offered in the buffet at 50mm or more on the 100mm VAS as palatable
- Medications that could influence appetite or sensory function
- Reports of metabolic or endocrine disease, gastrointestinal disorders, or history of medical or surgical events that could affect fat digestion and hormone signaling.
- Any chronic disease including type II diabetes, hypothyroidism, hyperthyroidism, cardiovascular disease, and cancer
- Any supplements that a subject begins taking between initiation of study and final testing.
- Anyone who is currently pregnant, lactating, or planning on becoming pregnant before the conclusion of this study.
- Anyone who has allergies to any of the components of the liquid meals
- Anyone who has donated blood in the last 20 days
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Texas Christian University
Fort Worth, Texas, 76102, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jada L Stevenson, PhD
Texas Christian University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- PREVENTION
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
November 8, 2016
First Posted
November 17, 2016
Study Start
October 1, 2016
Primary Completion
July 1, 2018
Study Completion
July 1, 2018
Last Updated
July 26, 2018
Record last verified: 2018-07
Data Sharing
- IPD Sharing
- Will not share