Comparation of Ultrasonic Imaging of Enthesopathy in Patients With Psoriatic Arthritis and Psoriasis

NCT02962271 | Unknown DMC

• 1 other identifier: ChinaPLAGH-PsA
• Study Type: observational
• Target: 187
• Locations: 1 country
• Sites: 1

Brief Summary

Psoriatic arthritis(PsA) and psoriasis(Ps) are two systemic inflammatory diseases linked with rash of psoriasis, but there's still great controversy regarding the exact relationship between them. Our study is to investigate the characteristics and differences of the ultrasonic imaging of enthesopathy in the lower extremity in patients with PsA and Ps, to explore the risk factors of Ps developing into PsA in the long term course.

Conditions

Enthesopathy

Keywords

Musculoskeletal Ultrasound; Psoriatic Arthritis; Enthesopathy

Outcome Measures

Primary Outcomes (1)

• The rate of enthesopathy comparison between psoriatic arthritis(PsA) and psoriasis(Ps) as assessed by SPSS v17.0

  up to 10 months

Secondary Outcomes (1)

• The potential risk factors of Ps for PsA as assessed by SPSS v17.0

  up to 10 months

Study Arms (2)

Psoriatic Arthritis

Musculoskeletal ultrasound (MSUS) of the lower limbs' entheses were performed

Device: Musculoskeletal Ultrasound

Psoriasis

Musculoskeletal ultrasound (MSUS) of the lower limbs' entheses were performed

Device: Musculoskeletal Ultrasound

Interventions

Musculoskeletal Ultrasound DEVICE

Musculoskeletal ultrasound (MSUS) of the lower limbs' entheses were performed

Psoriasis; Psoriatic Arthritis

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

A series of 44 patients with PsA, 44 age- and sex-matched patients of Ps and 44 HCs consecutively admitted from the outpatients clinic and ward from January 2016 to September 2016.

You may qualify if:

• Clinical diagnosis of plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis or osteoarthritis.
• Body Mass Index (BMI)\<30 kg/m2.
• Absence of local glucocorticoid or other drugs injection or surgical treatment for entheses scanned in the previous 6 weeks prior to clinical and musculoskeletal ultrasound (MSUS) evaluation.

You may not qualify if:

• Other systemic rheumatic diseases or malignant neoplasms.
• Peripheral neuropathy of lower extremity.

Sponsors & Collaborators

• Chinese PLA General Hospital: lead

Study Sites (1)

Chinese PLA General Hospital

Beijing, 100000, China

RECRUITING

MeSH Terms

Conditions

Enthesopathy; Arthritis, Psoriatic

Condition Hierarchy (Ancestors)

Tendinopathy; Muscular Diseases; Musculoskeletal Diseases; Tendon Injuries; Wounds and Injuries; Spondylarthropathies; Spondylarthritis; Spondylitis; Spinal Diseases; Bone Diseases; Arthritis; Joint Diseases; Psoriasis; Skin Diseases, Papulosquamous; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Jian Zhu

  Department of Rheumatology,PLA General Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Fei Sun

CONTACT

86-01-55499314; sunfeighy8911@163.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor

Study Record Dates

• First Submitted: November 3, 2016
• First Posted: November 11, 2016
• Study Start: January 1, 2016
• Primary Completion: November 1, 2016
• Study Completion: December 1, 2016
• Last Updated: November 11, 2016

Record last verified: 2016-11

Data Sharing

• IPD Sharing: Will share

Locations

CN (1)