the Effect of Dexmedetomidine in Coracoid Approach Brachial Plexus Block
1 other identifier
interventional
60
0 countries
N/A
Brief Summary
Dexmedetomidine is an α-2 adrenoreceptor agonist and has been extensively used through intravenous infusion，in order to improved the quality of block in regional anesthesia. In this prospective, randomized study, the authors focus on the effect of dexmedetomidine mixed with ropivacaine in coracoid approach brachial plexus block.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_4
Started Nov 2016
Shorter than P25 for phase_4
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 22, 2016
CompletedFirst Posted
Study publicly available on registry
November 11, 2016
CompletedStudy Start
First participant enrolled
November 12, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 30, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
May 25, 2017
CompletedFebruary 15, 2023
February 1, 2023
5 months
October 22, 2016
February 14, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
duration time
effective analgesia time
once per hour after surgery until 24 hours after surgery
Secondary Outcomes (2)
onset time
5,10,15,20,25,30 min after injection
Visual analogue scale
2,6,12,24hour after injection
Study Arms (2)
Group Control
EXPERIMENTAL40 ml 0.375% ropivacaine was injected after Locating brachial plexus.
Group Dexmedetomidine
EXPERIMENTAL40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.
Interventions
40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.
Eligibility Criteria
You may qualify if:
- American Society of Anesthesiologists (ASA) physical status I or II;
- Aged 18-60 years;
- The elbow, forearm, wrist or hand surgery
You may not qualify if:
- History of allergy to local anesthetics;
- Coagulation dysfunction, neuromuscular disease or local infection;
- The operation time is longer than the local anesthetics effective time.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
He WS, Liu Z, Wu ZY, Sun HJ, Yang XC, Wang XL. The effect of dexmedetomidine in coracoid approach brachial plexus block under dual stimulation. Medicine (Baltimore). 2018 Sep;97(39):e12240. doi: 10.1097/MD.0000000000012240.
PMID: 30278495DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
wensheng he, MD
Hebei Medical University
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 22, 2016
First Posted
November 11, 2016
Study Start
November 12, 2016
Primary Completion
March 30, 2017
Study Completion
May 25, 2017
Last Updated
February 15, 2023
Record last verified: 2023-02