NCT02954042

Brief Summary

The purpose of this investigation is to compare the clinical benefits of using the Pelvital product, in comparison to a sham procedure as a noninvasive treatment for female incontinence

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2017

Typical duration for not_applicable

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 28, 2016

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 3, 2016

Completed
4 months until next milestone

Study Start

First participant enrolled

March 10, 2017

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2019

Completed
Last Updated

April 14, 2021

Status Verified

April 1, 2021

Enrollment Period

2.6 years

First QC Date

October 28, 2016

Last Update Submit

April 13, 2021

Conditions

Keywords

Incontinence

Outcome Measures

Primary Outcomes (1)

  • Improvement in severity of involuntary urine loss

    Measured by pad testing

    Baseline, 6 weeks

Secondary Outcomes (2)

  • incontinence episode frequency

    Baseline, 6 weeks

  • health-related quality of life

    Baseline, 6 weeks

Study Arms (2)

Pelvital probe

EXPERIMENTAL

Probe to use for incontinence-Pevital is company name of product

Device: Pelvital probe

Placebo Probe

PLACEBO COMPARATOR

Placebo probe

Device: Placebo Probe

Interventions

Pelvital probe

Pelvital probe

Placebo Probe

Placebo Probe

Eligibility Criteria

Age18 Years - 75 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Female gender,
  • Ages 18-75,
  • Clinical diagnosis of stress urinary incontinence,
  • Ability to contract the pelvic floor muscles,
  • Able to document incontinence and voiding in a diary,
  • Provision of written informed consent form,
  • Minimum of 10 grams increase at initial 24-hour pad weight test

You may not qualify if:

  • Diagnosed mixed or urge urinary incontinence,
  • Impaired cognitive function or neurologic conditions
  • Physical limitations that impede the patient's ability to participate (e.g., ability to stand),
  • Acute infections or hematuria,
  • Pregnant or actively trying to conceive,
  • History of pelvic irradiation,
  • Concurrent medications with α-adrenergic antagonists or diuretics
  • Pelvic organ prolapse stage III or IV,
  • Severe urethral sphincter weakness and/or defect,
  • Suspected urethral and/or vesical fistula

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

University of Minnesota Medical Center

Maple Grove, Minnesota, 55369, United States

Location

Metro OBGYN

Maplewood, Minnesota, 55109, United States

Location

University of Minnesota Medical Center

Minneapolis, Minnesota, 55455, United States

Location

University of Washington Medical Center

Seattle, Washington, 98195, United States

Location

Related Publications (1)

  • Nakib N, Sutherland S, Hallman K, Mianulli M, R Boulware D. Randomized trial of mechanotherapy for the treatment of stress urinary incontinence in women. Ther Adv Urol. 2024 Feb 6;16:17562872241228023. doi: 10.1177/17562872241228023. eCollection 2024 Jan-Dec.

Study Officials

  • Nissrine Nakib, MD

    University of Minnesota

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 28, 2016

First Posted

November 3, 2016

Study Start

March 10, 2017

Primary Completion

October 30, 2019

Study Completion

October 30, 2019

Last Updated

April 14, 2021

Record last verified: 2021-04

Locations