Economic and Social Disparities and Breast Cancer
DESSEIN
Breast Cancer and Precariousness: Influence of Socio-demographic Inequalities in Cancer Stage at Diagnosis, Treatment Management and Rehabilitation in the Ile de France Area
2 other identifiers
observational
936
1 country
24
Brief Summary
Precariousness is a multifactorial concept that can be broken down in the form of economic insecurity, and / or social insecurity and / or territorial insecurity. Precariousness has an impact on health that is difficult to assess precisely because it also impacts on other factors that may themselves influence health. Therefore, the understanding of the impact of precariousness on health involves studying individuals in their context. Our study is designed to assess the impact of precariousness on the history of breast cancer, on care pathways, on treatment and rehabilitation in a multidisciplinary contextual analysis. Indeed, the socio -economic and geographical inequalities affect the history of breast cancer, treatment and its delay and post- treatment rehabilitation. The main objective of this project is to compare the stage of disease at diagnosis (according to the TNM classification) in deprived and non deprived patients. The secondary objectives are to compare in the two groups - the socio-economic and geographical inequalities - the direct and indirect costs related to the management, the out-of pocket costs and to describe, based on individual inequalities identified, the pathway of care of the patient. These objectives will be pursued in the framework of an observational cohort study, prospective, multicenter (Ile de France) comparative exposed / unexposed category. Each precarious patient will be matched to a non- precarious patient in the same age group, regardless of the center. The study will include any patient resident in Ile de France seeking treatment for breast cancer, regardless of the stage.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2016
Longer than P75 for all trials
24 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 26, 2016
CompletedFirst Posted
Study publicly available on registry
October 28, 2016
CompletedStudy Start
First participant enrolled
December 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 23, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
February 23, 2021
CompletedDecember 21, 2021
December 1, 2021
4.2 years
October 26, 2016
December 20, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
TNM stage
TNM classification according to initial clinical and radiological assessment
Baseline
Study Arms (2)
Precarious patients
Precarious patients - exposed - will be those identified as precarious by at least one of the three scores (EPICES, Pascal, European Deprivation Index)
Non precarious patients
Non precarious patient - non exposed - will be all the patients identified as non-precarious by the three scores (EPICES, Pascal, European Deprivation Index)
Interventions
Eligibility Criteria
Patients from Ile de France area having a breast cancer histologically proved and seeking for treatment. Any patient consulting for the first time in a specialized center for the treatment of breast cancer in Ile de France, whatever the stage of the disease, may potentially be recruited.
You may qualify if:
- \- Patients ? 18 years old having a breast cancer histologically proved
You may not qualify if:
- \- Patients with a history of cancer treated in the previous five years, or with another associated untreated cancer
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Assistance Publique - Hôpitaux de Parislead
- National Cancer Institute, Francecollaborator
- Paris West University Nanterre La Défensecollaborator
- Paris 12 Val de Marne Universitycollaborator
- Fondation Ophtalmologique Adolphe de Rothschildcollaborator
Study Sites (24)
Centre Hopitalier Victor Dupouy Argenteuil
Argenteuil, France
Hôpital Jean Verdier
Bondy, 94143, France
Centre Hospitalier de Pontoise
Cergy-Pontoise, France
Hopital Privé Paule Egine
Champigny-sur-Marne, France
CH Sud Francilien
Corbeil-Essonnes, France
Centre Hospitalier Intercommunal Créteil
Créteil, 94000, France
Hôpital Henri Mondor
Créteil, 94010, France
Clinique Claude Bernard
Ermont, France
CH de Lagny sur Marne
Lagny-sur-Marne, 77400, France
Hôpital Bicêtre
Le Kremlin-Bicêtre, France
Institut de Cancérologie Hartmann
Levallois-Perret, 92300, France
Institut Curie Hôpital de Paris
Paris, 75005, France
Hôpital Lariboisière
Paris, 75010, France
Hôpital Saint-Louis
Paris, 75010, France
Hôpital Privé des Peupliers
Paris, 75013, France
HEGP
Paris, 75015, France
Hôpital Tenon
Paris, 75020, France
Groupe Hospitalier Paris Saint-Joseph
Paris, France
Centre Hospitalier Intercommunal Poissy Saint Germain en Laye
Poissy, 78300, France
Institut Curie Hôpital René-Huguenin site Saint-Cloud
Saint-Cloud, 92210, France
Centre Hospitalier Delafontaine
Saint-Denis, 93200, France
Institut de cancérologie Paris Nord
Sarcelles, France
Clinique de l'Estrée
Stains, France
Centre Hospitalier de Versailles
Versailles, 78157, France
Related Publications (1)
Ngo C, Dinut A, Bochaton A, Charreire H, Despres C, Baffert S, Lecuru F, Chatellier G. From prospective clinical trial to reducing social inequalities in health: The DESSEIN trial, concept and design of a multidisciplinary study in precarious patients with breast cancer. BMC Public Health. 2019 Nov 4;19(1):1450. doi: 10.1186/s12889-019-7611-6.
PMID: 31684919DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Charlotte NGO, MD
AP - HP, Hôpital Européen Georges-Pompidou, Paris, France
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 26, 2016
First Posted
October 28, 2016
Study Start
December 1, 2016
Primary Completion
February 23, 2021
Study Completion
February 23, 2021
Last Updated
December 21, 2021
Record last verified: 2021-12