NCT02943980

Brief Summary

A randomized controlled prospective study of laryngoscopy and evaluation of the Intraoperative nerve monitoring during thyroid surgery comparing direct laryngoscopy and the C-MAC videolaryngoscope.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
260

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 13, 2016

Completed
12 days until next milestone

First Posted

Study publicly available on registry

October 25, 2016

Completed
2 months until next milestone

Study Start

First participant enrolled

January 3, 2017

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2018

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 15, 2019

Completed
Last Updated

May 17, 2022

Status Verified

May 1, 2022

Enrollment Period

1.3 years

First QC Date

October 13, 2016

Last Update Submit

May 14, 2022

Conditions

Keywords

Intraoperative nerve monitoring, airway management

Outcome Measures

Primary Outcomes (1)

  • Evaluation of the quality of the IONM during thyroid surgery

    Evaluation of intraoperative loss of the EMG-Signal (Quality character of the IONM)

    Quality IONM; intraoperative 1-3 hours

Secondary Outcomes (4)

  • intubation success

    at intubation; < 120 Seconds

  • Cormack and Lehane Classification

    during the laryngoscopy; < 120 Seconds

  • Percentage of glottic opening

    during the laryngoscopy; < 120 Seconds

  • IDS (intubation difficult score)

    < 120 Seconds

Study Arms (2)

CMAC Videolaryngoscope

EXPERIMENTAL

tracheal intubation using CMAC

Device: CMAC Videolaryngoscope

Macintosh laryngoscope

EXPERIMENTAL

tracheal intubation using Macintosh laryngoscope

Device: Macintosh Laryngoscope

Interventions

In a randomised order we evaluate the quality of the IONM after securing the airway with the CMAC

CMAC Videolaryngoscope

In a randomised order we evaluate the quality of the IONM after securing the airway with the conventional Macintosh Laryngoscope

Macintosh laryngoscope

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥ 18 Years No concurrent participation in another study
  • capacity to consent
  • Present written informed consent of the research participant
  • Elective surgery under general anesthesia

You may not qualify if:

  • Age \<18 years
  • Existing pregnancy
  • Lack of consent
  • inability to consent
  • emergency patients
  • Emergency situations in the context of a Difficult Airway Management
  • ASA classification 4
  • situations where the possibility of accumulated gastric contents
  • Participation in another study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Anesthesiology,Prof. C. Werner, Universitätsmedizin of the JG University

Mainz, Rhineland-Palatinate, D55131, Germany

Location

MeSH Terms

Conditions

Thyroid Diseases

Condition Hierarchy (Ancestors)

Endocrine System Diseases

Study Officials

  • Marc Kriege, MD

    University Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

October 13, 2016

First Posted

October 25, 2016

Study Start

January 3, 2017

Primary Completion

May 1, 2018

Study Completion

February 15, 2019

Last Updated

May 17, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share

Locations