A Comparison of Protein Intake Between ERAS and Conventional Care After Elective Colorectal Surgery
Higher Protein Intakes Are Associated With Reduced Length of Stay: A Comparison Between ERAS and Conventional Care After Elective Colorectal Surgery
1 other identifier
observational
115
0 countries
N/A
Brief Summary
The primary objective of this prospective cohort study is to compare protein intake and adequacy between patients receiving Enhanced Recovery After Surgery (ERAS) protocols with patients receiving conventional care. The study will also compare energy intakes, gut function, and clinical outcomes between groups. The ability of nutritional parameters, including preoperative malnutrition risk and postoperative protein intake, to predict length of hospital stay will be evaluated.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Mar 2014
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2016
CompletedFirst Submitted
Initial submission to the registry
October 14, 2016
CompletedFirst Posted
Study publicly available on registry
October 21, 2016
CompletedMay 3, 2017
May 1, 2017
1.1 years
October 14, 2016
May 1, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Total protein intake (grams) as assessed by food records.
Protein intake from food records on postoperative days 1, 2 and 3 will be recorded. Patients will record the amount of food, fluid, and oral nutrition supplements consumed using quartiles (none, ¼, ½, ¾, all) on a food record. Research staff will verify the self-reported food records with the patients after each meal. Total protein intake in grams will be determined by comparing actual food intake (obtained from the food records) to the food composition records of our institution.
Average in first three postoperative days
Secondary Outcomes (1)
Length of hospital stay (number of days)
Number of days spent in hospital during admission for surgery up to 6 months
Study Arms (2)
Enhanced Recovery After Surgery (ERAS)
ERAS group followed the ERAS protocol. The protocol was implemented 13 months prior to the start of data collection.
Conventional
Conventional group received conventional care.
Interventions
Patients in the ERAS group received the ERAS protocol
Eligibility Criteria
Colorectal surgery
You may qualify if:
- adult patients ≥18 years of age
- elective colorectal resection
You may not qualify if:
- co-morbidities that could have interfered with oral intake (e.g., dysphagia)
- concurrent enteral or parenteral nutrition prior to surgery were excluded since food intakes could be influenced by these conditions.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Yeung SE, Hilkewich L, Gillis C, Heine JA, Fenton TR. Protein intakes are associated with reduced length of stay: a comparison between Enhanced Recovery After Surgery (ERAS) and conventional care after elective colorectal surgery. Am J Clin Nutr. 2017 Jul;106(1):44-51. doi: 10.3945/ajcn.116.148619. Epub 2017 May 3.
PMID: 28468890DERIVED
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
October 14, 2016
First Posted
October 21, 2016
Study Start
March 1, 2014
Primary Completion
April 1, 2015
Study Completion
May 1, 2016
Last Updated
May 3, 2017
Record last verified: 2017-05
Data Sharing
- IPD Sharing
- Will not share