NCT02939885

Brief Summary

The purpose of the study is to better define and understand the brain mechanisms related to emotional and cognitive dimensions using odorous stimuli, gustatory stimuli, visual stimuli and auditory stimuli using functional Magnetic Resonance Imaging (fMRI).

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2006

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2006

Completed
9.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

September 5, 2016

Completed
2 months until next milestone

First Posted

Study publicly available on registry

October 20, 2016

Completed
Last Updated

October 20, 2016

Status Verified

October 1, 2016

Enrollment Period

9.9 years

First QC Date

September 5, 2016

Last Update Submit

October 19, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Cerebral activation of subjects using Blood Oxygenation Level Dependant (BOLD) contrast imaging

    measure brain activity by the BOLD technical

    at admission

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants came after invitation to volunteer. They are mainly students from our university.

You may qualify if:

  • right-handed
  • Healthy Volunteers

You may not qualify if:

  • those applied for an magnetic resonance examination

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (7)

  • Bonnet L, Comte A, Tatu L, Millot JL, Moulin T, Medeiros de Bustos E. The role of the amygdala in the perception of positive emotions: an "intensity detector". Front Behav Neurosci. 2015 Jul 7;9:178. doi: 10.3389/fnbeh.2015.00178. eCollection 2015.

  • Comte A, Gabriel D, Pazart L, Magnin E, Cretin E, Haffen E, Moulin T, Aubry R. On the difficulty to communicate with fMRI-based protocols used to identify covert awareness. Neuroscience. 2015 Aug 6;300:448-59. doi: 10.1016/j.neuroscience.2015.05.059. Epub 2015 May 30.

  • Gabriel D, Henriques J, Comte A, Grigoryeva L, Ortega JP, Cretin E, Brunotte G, Haffen E, Moulin T, Aubry R, Pazart L. Substitute or complement? Defining the relative place of EEG and fMRI in the detection of voluntary brain reactions. Neuroscience. 2015 Apr 2;290:435-44. doi: 10.1016/j.neuroscience.2015.01.053. Epub 2015 Jan 30.

  • Pazart L, Comte A, Magnin E, Millot JL, Moulin T. An fMRI study on the influence of sommeliers' expertise on the integration of flavor. Front Behav Neurosci. 2014 Oct 16;8:358. doi: 10.3389/fnbeh.2014.00358. eCollection 2014.

  • Galliot E, Comte A, Magnin E, Tatu L, Moulin T, Millot JL. Effects of an ambient odor on brain activations during episodic retrieval of objects. Brain Imaging Behav. 2013 Jun;7(2):213-9. doi: 10.1007/s11682-012-9218-8.

  • Billot PE, Comte A, Galliot E, Andrieu P, Bonnans V, Tatu L, Gharbi T, Moulin T, Millot JL. Time course of odorant- and trigeminal-induced activation in the human brain: an event-related functional magnetic resonance imaging study. Neuroscience. 2011 Aug 25;189:370-6. doi: 10.1016/j.neuroscience.2011.05.035. Epub 2011 May 20.

  • Lombion S, Comte A, Tatu L, Brand G, Moulin T, Millot JL. Patterns of cerebral activation during olfactory and trigeminal stimulations. Hum Brain Mapp. 2009 Mar;30(3):821-8. doi: 10.1002/hbm.20548.

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 5, 2016

First Posted

October 20, 2016

Study Start

January 1, 2006

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

October 20, 2016

Record last verified: 2016-10