NCT02936518

Brief Summary

A previously published study (https://www.ncbi.nlm.nih.gov/pubmed/27641715) identified breastfeeding improvements following lingual frenotomy and/or maxillary labial frenectomy. In the previous cohort, babies were excluded from the study if they had previously undergone an attempted frenotomy prior to seeing the P.I. in the office. The proposed study will only look at those babies who did undergo a previous frenotomy to determine:

  1. 1.the presence of continued problematic breastfeeding symptoms
  2. 2.if further tongue tie or lip tie release improves those outcomes

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
55

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2014

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2014

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2015

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

October 14, 2016

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 18, 2016

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

September 20, 2017

Status Verified

September 1, 2017

Enrollment Period

10 months

First QC Date

October 14, 2016

Last Update Submit

September 19, 2017

Conditions

Keywords

ankyloglossiabreastfeedinglip tie

Outcome Measures

Primary Outcomes (3)

  • Nipple pain

    1 week post-procedure

  • Reflux (i-GERQ-R)

    1 week and 1 month post-procedure

  • Maternal breastfeeding self-efficacy (BSES-SF)

    1 week and 1 month post-procedure

Study Arms (1)

Intervention

EXPERIMENTAL
Procedure: Lingual frenotomy and/or maxillary labial frenectomy

Interventions

Eligibility Criteria

Age1 Day - 8 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Healthy babies who are breastfeeding
  • Had a previous frenotomy prior to presenting to the P.I.

You may not qualify if:

  • Twins, triplets
  • Maternal breast surgery or IGT
  • Premature birth
  • Significant heart/lung/brain disease of infant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (3)

  • O'Callahan C, Macary S, Clemente S. The effects of office-based frenotomy for anterior and posterior ankyloglossia on breastfeeding. Int J Pediatr Otorhinolaryngol. 2013 May;77(5):827-32. doi: 10.1016/j.ijporl.2013.02.022. Epub 2013 Mar 22.

    PMID: 23523198BACKGROUND
  • Geddes DT, Langton DB, Gollow I, Jacobs LA, Hartmann PE, Simmer K. Frenulotomy for breastfeeding infants with ankyloglossia: effect on milk removal and sucking mechanism as imaged by ultrasound. Pediatrics. 2008 Jul;122(1):e188-94. doi: 10.1542/peds.2007-2553. Epub 2008 Jun 23.

    PMID: 18573859BACKGROUND
  • Ghaheri BA, Cole M, Fausel SC, Chuop M, Mace JC. Breastfeeding improvement following tongue-tie and lip-tie release: A prospective cohort study. Laryngoscope. 2017 May;127(5):1217-1223. doi: 10.1002/lary.26306. Epub 2016 Sep 19.

    PMID: 27641715BACKGROUND

MeSH Terms

Conditions

AnkyloglossiaBreast Feedinglip tie

Condition Hierarchy (Ancestors)

Stomatognathic DiseasesFeeding BehaviorBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Otolaryngologist/Head and Neck Surgeon

Study Record Dates

First Submitted

October 14, 2016

First Posted

October 18, 2016

Study Start

June 1, 2014

Primary Completion

April 1, 2015

Study Completion

June 1, 2017

Last Updated

September 20, 2017

Record last verified: 2017-09