NCT02931617

Brief Summary

Two forms of pre and postoperative physiotherapy are compared in three cohorts of patients undergoing cardio-thoracic surgery: Minor thoracic surgery (biopsy), major thoracic surgery (lobectomy etc, open or VATS) and cardiac surgery

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2013

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2013

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

December 9, 2015

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2016

Completed
7 months until next milestone

First Posted

Study publicly available on registry

October 13, 2016

Completed
Last Updated

October 13, 2016

Status Verified

October 1, 2016

Enrollment Period

2.5 years

First QC Date

December 9, 2015

Last Update Submit

October 10, 2016

Conditions

Outcome Measures

Primary Outcomes (4)

  • Change in FEV1

    Serial measurements

    Preop + 1-3 postoperative days

  • Number of patients with atelectasis

    In chest x-ray

    Preop + 1-3 postoperative days

  • Change in peripheral oxygen saturation

    Serial measurements

    Preop + 1-3 postoperative days

  • Postoperative lung complications

    Number of patients with lung infections, prolonged air leak, pneumothorax

    Preop + 1-30 postoperative days

Secondary Outcomes (1)

  • Compliance to Chest physiotherapy

    Preop + 1-3 postoperative days

Study Arms (2)

Physiotherapy w/Positive end expiratory pressure training

ACTIVE COMPARATOR

Chest Physiotherapy w/Positive end expiratory pressure training; post therapy lung volume measurements

Other: Chest PhysiotherapyDevice: Post-therapy lung volume measurements

Physiotherapy w/Inspiratory force training

EXPERIMENTAL

Chest Physiotherapy w/Inspiratory force training; post therapy lung volume measurements

Other: Chest PhysiotherapyDevice: Post-therapy lung volume measurements

Interventions

Physiotherapy w/Inspiratory force trainingPhysiotherapy w/Positive end expiratory pressure training

In both intervention groups.

Physiotherapy w/Inspiratory force trainingPhysiotherapy w/Positive end expiratory pressure training

Eligibility Criteria

Age16 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • cardiothoracic operation,
  • informed consent

You may not qualify if:

  • reduced co-operation (such as psychiatric diagnosis),
  • severe neurologic disease affecting respiratory function,
  • alcohol or drug abuse at hospital entry,
  • tuberculosis or other contagious lung infection,
  • severe respiratory insufficiency SpO2 \< 90 or blood pO2 \<8 or rep.rate \> 25/min at rest or supplementary oxygen required at home,
  • cardiac pacemaker.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tampere University Hospital, Heart Center

Tampere, 33521, Finland

Location

Related Publications (1)

  • Lahteenmaki S, Juutinen M, Viik J, Mahrberg H, Laurikka J. Effects of physiotherapy on breathing cycle after thoracic surgery measured with impedance pneumography in a prospective clinical comparison. Gen Thorac Cardiovasc Surg. 2025 Sep 26. doi: 10.1007/s11748-025-02199-y. Online ahead of print.

Study Officials

  • Jari O Laurikka, MD,PhD

    Tampere Univeristy Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 9, 2015

First Posted

October 13, 2016

Study Start

September 1, 2013

Primary Completion

March 1, 2016

Study Completion

April 1, 2016

Last Updated

October 13, 2016

Record last verified: 2016-10

Locations