Analgesic Use and Effectiveness for Dental Procedures

NCT02929602 | Completed DMC

• 2 other identifiers: PRL0706U01DE016755
• Study Type: observational
• Target: 2,773
• Locations: 1 country
• Sites: 1

Brief Summary

Opioid analgesics prescribed by dentists may contribute to the larger national issue of the use and abuse of the drug. On occasion dental pain may be sufficiently severe to support the use of opioids. This study used both dentist and patient input to evaluate the use of opioid and over-the-counter analgesics following one of seven coded common dental procedures. The study includes a five day patient follow up assessment of the effectiveness of the analgesic. Baseline questionnaires were completed by eligible participants, and they responded to the day 5 follow up questionnaires.

Conditions

Pain

Keywords

prescribing; effectiveness; dental; opioid; analgesic

Outcome Measures

Primary Outcomes (1)

• Dentist questionnaire

  dentists' postprocedural prescriptions were recorded by analgesic class: Opioid, NSAID, or other (Descriptive measures)

  baseline

Secondary Outcomes (2)

• Dentist questionnaire - anticipated pain by patients using VAS-5 pain scale

  5 days after the dental procedure

• Patient questionnaire - OHIP-14 patient reported outcomes quality of life survey (questionnaire).

  5 days after the dental procedure

Other Outcomes (1)

• Patient questionnaire - side effects of analgesics post dental procedure

  5 days post dental procedure

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Practice-based study. Patients recruited from the practice sites of PEARL Network dentists.

You may qualify if:

• Presence of erupted second molar teeth.
• Scheduled for treatment in one procedure of the following six procedure classes:
• extraction, endodontic therapy, pulp capping, crown preparation, periodontal surgery, abscess treatment
• Expected by the P-I to experience postoperative pain sufficient to require an analgesic
• Permanent dentition (erupted 2nd molar teeth)
• Capacity to judge pain level
• Ability and willingness to give verbal consent

You may not qualify if:

• Under treatment for medical disorders, including dementia, Parkinson's disease, depression, severe anxiety, or any other medical condition, that, in the opinion of the P-I, would affect the subject's judgment of postoperative pain
• Current participation in another dental or medical research study.

Sponsors & Collaborators

• Pearl Network: lead
• National Institute of Dental and Craniofacial Research (NIDCR): collaborator

Study Sites (1)

PEARL Network Sites

New York, New York, 10010, United States

Location

Related Publications (1)

• Wong YJ, Keenan J, Hudson K, Bryan H, Naftolin F, Thompson VP, Craig RG, Vena D, Collie D, Wu H, Matthews AG, Grill AC, Curro FA. Opioid, NSAID, and OTC Analgesic Medications for Dental Procedures: PEARL Network Findings. Compend Contin Educ Dent. 2016 Nov/Dec;37(10):710-718.

  PMID: 27875056 DERIVED

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Frederick A Curro, DMD, PhD

  Pearl Network

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 5, 2016
• First Posted: October 11, 2016
• Study Start: June 1, 2007
• Primary Completion: November 1, 2011
• Study Completion: June 1, 2014
• Last Updated: October 11, 2016

Record last verified: 2016-10

Data Sharing

• IPD Sharing: Will share

Locations

US (1)