NCT02926300

Brief Summary

The purpose of this clinical trial is to evaluate long-term safety and efficacy in patients who has history of FURESTEM-CD injection at least once.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
24

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2015

Longer than P75 for all trials

Geographic Reach
1 country

7 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2015

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

November 11, 2015

Completed
11 months until next milestone

First Posted

Study publicly available on registry

October 6, 2016

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2021

Completed
Last Updated

September 6, 2017

Status Verified

September 1, 2016

Enrollment Period

5.9 years

First QC Date

November 11, 2015

Last Update Submit

September 5, 2017

Conditions

Keywords

crohn's diseasestem cell therapyinflammatory bowel diseasehUCB-MSCUCB-MSCUmbilical cord BloodRheumatoid ArthritisRAStem cellCell therapyFurestemMesenchymal stem cellMSC

Outcome Measures

Primary Outcomes (1)

  • all kinds of adverse events which occur during the clinical sutdy

    Safety outcome

    114 weeks

Secondary Outcomes (2)

  • ratio of patients who is applicable to CDAI<150

    114 weeks

  • ratio of patients who reduce CDAI over 70 as contrasted witd baseline(V7)

    114 weeks

Interventions

stem cellsBIOLOGICAL

IV infusion

Also known as: FURESTEM-CD Inj.

Eligibility Criteria

Age19 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Gender: Both Age Limits: 19years to 70years Healthy Volunteers?: No.

You may qualify if:

  • patients who has history of FURESTEM-CD Inj. injection at least once.
  • patients who understand and voluntarily sign an informed consent form.

You may not qualify if:

  • any other condition which the Principle Investigator judges would make subject unsuitable for study participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Inje University Haeundae Paik Hospital

Busan, 48108, South Korea

RECRUITING

Yeungnam University Medical Center

Daegu, 42415, South Korea

RECRUITING

Seoul National Universtiy Bundang Hospital

Seongnam-si, 13620, South Korea

RECRUITING

Severance Hospital

Seoul, 03722, South Korea

RECRUITING

Asan Medical Center

Seoul, 138-736, South Korea

RECRUITING

Soeul National University Hospital

Soeul, 110-7441, South Korea

RECRUITING

The Catholic University of Korea, St. Vincent'S Hospital.

Suwon, 16247, South Korea

RECRUITING

MeSH Terms

Conditions

Crohn DiseaseInflammatory Bowel DiseasesArthritis, Rheumatoid

Condition Hierarchy (Ancestors)

GastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal DiseasesArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Suk-kyun Yang

    Asan Medical Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Eun-ji Kang

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 11, 2015

First Posted

October 6, 2016

Study Start

November 1, 2015

Primary Completion

October 1, 2021

Study Completion

November 1, 2021

Last Updated

September 6, 2017

Record last verified: 2016-09

Locations