Impact of Non-traditional Guitar Group Instruction on Functional Movement and Well-being in Parkinson's Disease Patients

NCT02925065 | Completed

• 1 other identifier: IRB00091797
• Study Type: interventional
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

This controlled prospective cohort study is designed to assess the feasibility and effect of twice-weekly 60 minute non-traditional guitar classes on PD patient's self-reported and measurable outcomes including upper extremity function, motor findings, quality of life, mood, and cognitive findings. 24-30 individuals with PD will be randomly assigned to an early-start and a late-start guitar instruction group. Prior to conducting a larger study, this study seeks to assess the possibility that participation in an instrumental performance activity in a group setting may improve outcomes in PD patients.

Conditions

Parkinson's Disease

Keywords

Parkinson's; Non-traditional guitar instruction; Guitar therapy; Upper extremity motor function; Hand dexterity

Outcome Measures

Primary Outcomes (1)

• Feasibility

  Percentage of study completion will be used to assess feasibility of the intervention along with descriptive statistics. The study will be deemed feasible if 80% of participants complete 10 or more guitar group interventions. The factors that affect probability of attending guitar classes will also be investigated.

  6 weeks

Secondary Outcomes (10)

• Efficacy: Quality of Life

  6 weeks and 12 week follow up

• Upper extremity motor function

  6 weeks and 12 weeks follow up

• Fine manual dexterity

  6 weeks and 12 weeks follow up

• Gross manual dexterity

  6 weeks and 12 weeks follow up

• Upper extremity activities of daily living function

  6 weeks and 12 weeks follow up

Study Arms (2)

Early-start guitar instruction group

EXPERIMENTAL

A 6 week twice-weekly non-traditional group guitar instruction will be implemented in addition to usual treatment between weeks 1-6 of the study.

Other: Non-traditional group guitar instruction

Delayed-start guitar instruction group

EXPERIMENTAL

A 6 week twice-weekly non-traditional group guitar instruction will be implemented in addition to usual treatment between weeks 8-13 of the study.

Other: Non-traditional group guitar instruction

Interventions

Non-traditional group guitar instruction OTHER

A 6-week curriculum for non-traditional training in finger-style guitar has been developed with rhythmic and goal oriented upper extremity and finger movements. Guitar group intervention will be implemented at the Towson campus of the Peabody Preparatory. Intervention approaches will include rhythmic digital grip with finger isolation, goal directed rhythmic reach on the fret-board and rhythmic alternating tap-like digit and hand movements on the guitar. Participants will be provided with the instruments in the group setting without expectation of practice at home.

Delayed-start guitar instruction group; Early-start guitar instruction group

Eligibility Criteria

• Age: 18 Years - 89 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult patients (age 18-89) with idiopathic PD diagnosis according to the United Kingdom (UK) Brain Bank Criteria with bilateral motor symptoms.
• Hoehn and Yahr Stages 1-3.
• MoCA score \>24 to screen out patients with dementia.

You may not qualify if:

• Prior exposure to guitar training.
• History of prior trauma of the brain or upper extremities.
• Inability to personally consent to study.
• Inability or unwillingness to participate in twice weekly classes for 6 weeks.
• Agitation or hallucinations.

Sponsors & Collaborators

• Johns Hopkins University: lead

Study Sites (1)

Johns Hopkins University (Peabody Institute & Department of Neurology)

Baltimore, Maryland, 21202, United States

Location

Related Publications (23)

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  BACKGROUND

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Serap E Bastepe-Gray, MD, MM, MsOT

  Johns Hopkins University

  PRINCIPAL INVESTIGATOR

• Alexander Pantelyat, MD

  Johns Hopkins University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants will be randomly assigned to early-start or late start guitar groups. Following baseline assessment week, the early-start group will receive twice-weekly non traditional guitar instruction for 6 weeks. The late-start guitar group will receive same intervention after the early-start group complete their 6 week instruction. Study assessments will be conducted during week 7 and week 14. Follow up assessment will be conducted in week 20.

Study Record Dates

• First Submitted: October 4, 2016
• First Posted: October 5, 2016
• Study Start: March 5, 2018
• Primary Completion: June 7, 2018
• Study Completion: July 26, 2018
• Last Updated: October 2, 2018

Record last verified: 2018-09

Locations

US (1)