Effect of Critical Patients Mobilization on Respiratory and Peripheral Muscle Strength and Functional Capacity.

NCT02919085 | Completed

• 1 other identifier: 01110031483
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

To analyze changes on respiratory muscle strength, peripheral and functional capacity of critically ill patients with clinical and surgical etiology, breathing spontaneously and bedridden, within 48 hours of admission to the intensive care unit (ICU) and if there are correlations among these variables. This is an observational study. Respiratory muscle strength will be assessed through the maximum inspiratory pressure (MIP) and maximal expiratory pressure (MEP) and peripheral muscle strength, by the Medical Research Council score (MRC) and hand grip test and functional capacity through the Functional Independence Measure (FIM) and Physical Function ICU Test Score (PFIT-s) in the period between 24h and 48h of hospitalization in the adult ICU. For descriptive purposes, the sample will be stratified according to clinical and surgical characteristics. Correlations will be determined using the Pearson test, with significance level of p \<0.05.

Conditions

Intensive Care Unit Syndrome; Muscle Weakness

Outcome Measures

Primary Outcomes (3)

• Respiratory muscle strength

  Respiratory muscle strength will be assessed through the maximum inspiratory pressure (MIP) and maximal expiratory pressure (MEP).

  48 hours

• Peripheral muscle strength

  The peripheral muscle strength will be assessed through the Medical Research Council score (MRC) and hand grip test.

  48 hours

• Functional capacity

  The functional capacity will be assessed through the Functional Independence Measure (FIM) and Physical Function ICU Test Score (PFIT-s).

  48 hours

Study Arms (1)

Mobilization

EXPERIMENTAL

Procedure: Early ambulation

Interventions

Early ambulation PROCEDURE

Procedure to accelerate the ability of a patient to walk or move about by reducing the time to ambulation. It is characterized by a shorter period of hospitalization or recumbency than is normally practiced.

Also known as: Early mobilization

Mobilization

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Breathing spontaneously
• Length of stay in ICU greater than 24 hours
• Adherence to study

You may not qualify if:

• Patients with poor prognosis or palliation;
• Preexisting neuromuscular diseases;
• Immobility or restriction to bed prior to admission;
• Nonunions and amputations;
• Osteomioarticular, cognitive or neurological impairment;
• Non-cooperation;
• Specific contraindications to the application of evaluation methods;
• Hemodynamic or respiratory instability within 48 hours of ICU admission preventing evaluation muscle strength and functional capacity.

Sponsors & Collaborators

• Universidade Federal de Pernambuco: lead

Study Sites (1)

Real Hospital Português de Beneficência

Recife, Pernambuco, 52010-902, Brazil

Location

Related Publications (3)

• Williams TA, Dobb GJ, Finn JC, Webb SA. Long-term survival from intensive care: a review. Intensive Care Med. 2005 Oct;31(10):1306-15. doi: 10.1007/s00134-005-2744-8. Epub 2005 Aug 24.

  PMID: 16132895 RESULT

• Rossi PJ, Edmiston CE Jr. Patient safety in the critical care environment. Surg Clin North Am. 2012 Dec;92(6):1369-86. doi: 10.1016/j.suc.2012.08.007. Epub 2012 Oct 6.

  PMID: 23153874 RESULT

• Neideen T. Monitoring devices in the intensive care unit. Surg Clin North Am. 2012 Dec;92(6):1387-402. doi: 10.1016/j.suc.2012.08.010. Epub 2012 Oct 13.

  PMID: 23153875 RESULT

MeSH Terms

Conditions

Muscle Weakness

Interventions

Early Ambulation

Condition Hierarchy (Ancestors)

Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics

Study Officials

• Maria KF Richtrmoc

  Universidade Federal de Pernambuco

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Master student

Study Record Dates

• First Submitted: September 23, 2016
• First Posted: September 29, 2016
• Study Start: December 1, 2016
• Primary Completion: October 1, 2017
• Study Completion: December 1, 2017
• Last Updated: August 26, 2021

Record last verified: 2021-08

Locations

BR (1)