Trials Sponsors Conditions Drugs Pricing

Conditions

Type 1 Diabetes Mellitus

Keywords

Pancreatic islet transplantation

Outcome Measures

Primary Outcomes (1)

Absence of ophthalmic complications
safety
90 days

Secondary Outcomes (5)

Change in insulin production
90 days
Change in insulin requirements
90 days
Change in HbA1c
90 days
Change in fasting glucose
90 days
Change in total number of hypoglycemic events
90 days

Study Arms (1)

Pancreatic islet transplantation

EXPERIMENTAL

Pancreatic islet transplantation in the anterior chamber of the human eye

Procedure: Pancreatic islet transplantation in the anterior chamber

Interventions

Pancreatic islet transplantation in the anterior chamberProcedure

Transplantation of allogeneic pancreatic islet cells into the anterior chamber of a severely visual impaired diabetic human eye

Pancreatic islet transplantation

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Type 1 Diabetes (American Diabetes Association criteria)
Kidney transplant recipient with ongoing immunosuppression

Sponsors & Collaborators

University Hospital, Basel, Switzerland
Otherlead

Study Sites (1)

University Hospital Basel

Basel, 4031, Switzerland

RECRUITING

Marc Y Donath, Prof.CONTACT0041 61 265 50 78 marc.donath@usb.ch

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Interventions

Islets of Langerhans Transplantation

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

Cell TransplantationCell- and Tissue-Based TherapyBiological Therapy

Study Officials

Marc Y Donath, Prof.
University Hospital, Basel, Switzerland
PRINCIPAL INVESTIGATOR

Central Study Contacts

Marc Y Donath, Prof.

CONTACT

0041 61 265 50 78 marc.donath@usb.ch

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

March 31, 2016

First Posted

September 27, 2016

Study Start

March 2016

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

April 2025

Estimated (date passed)

Pancreatic Islet Transplantation in the Anterior Chamber of the Human Eye - a Pilot Study

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (5)

Study Arms (1)

Pancreatic islet transplantation

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (5)

Study Arms (1)

Pancreatic islet transplantation

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations