NCT02909647

Brief Summary

Background: Three dimensional (3D) digital pre-operative planning software for osteosynthesis of fractures was developed. To assess the usefulness of the 3D planning, we evaluated the accuracy of the reduction shapes and selected implants in the patients with distal radius fractures. Methods: Thirty wrists of 30 distal radius fracture patients who underwent osteosynthesis using volar locking plates were evaluated. Fifteen wrists were treated with 3D preoperative planning as the plan group. The other fifteen wrists were treated with conventional preoperative planning as the control group. Volar tilt and radial inclination were measured after operation and compared with the healthy side wrist. In addition, preoperative planning and postoperative reductions were compared by measuring the volar tilt and radial inclination of the 3D images in the plan group. The intra-class correlation coefficient (ICC) values of the radiological parameters between healthy side wrists and injured side wrists, between preoperative planning and postoperative reductions were evaluated. For the accuracy of the implant choices, the ICCs for the screw lengths between the preoperative plan and the actual choices were evaluated in the plan group.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

September 14, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 21, 2016

Completed
7.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2024

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2025

Completed
Last Updated

April 27, 2022

Status Verified

April 1, 2022

Enrollment Period

10.3 years

First QC Date

September 14, 2016

Last Update Submit

April 25, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Intraclass correlation coefficients between preoperative plan and after surgery

    An intra-class correlation coefficient (ICC) was used to evaluate the accuracy of the anatomical reduction. The ICC values of the radiological parameters (volar tilt and radial inclination) between healthy side wrists and injured side wrists after the surgery were evaluated in both the plan and control groups. In addition, the ICCs of the 3D measurements between the pre-operative plan and the post-operative 3D images were evaluated in the plan group.

    1 week

Study Arms (2)

Plan group

ACTIVE COMPARATOR

3D preoperative planning for the distal radius fracture was performed prior to the osteosynthesis.

Procedure: Preoperative planningProcedure: Osteosynthesis

Control group

ACTIVE COMPARATOR

Conventional preoperative planning for the distal radius fracture was performed prior to the osteosynthesis.

Procedure: Preoperative planningProcedure: Osteosynthesis

Interventions

preoperative planning using 3D digital planning software or conventional template

Control groupPlan group

osteosynthesis using volar locking plate

Control groupPlan group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • the patients who have distal radius fracture in their unilateral wrist.

You may not qualify if:

  • the patients who reported a previous history of traumatic injuries to the arm.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tokyo Medical University Ibaraki Medical Center

Ami, Ibaraki, 300-0395, Japan

RECRUITING

Related Publications (1)

  • Yoshii Y, Ogawa T, Shigi A, Oka K, Murase T, Ishii T. Three-dimensional evaluations of preoperative planning reproducibility for the osteosynthesis of distal radius fractures. J Orthop Surg Res. 2021 Feb 12;16(1):131. doi: 10.1186/s13018-021-02278-9.

MeSH Terms

Conditions

Wrist Fractures

Interventions

Fracture Fixation, Internal

Condition Hierarchy (Ancestors)

Wrist InjuriesArm InjuriesWounds and InjuriesFractures, Bone

Intervention Hierarchy (Ancestors)

Fracture FixationOrthopedic ProceduresTherapeuticsSurgical Procedures, Operative

Study Officials

  • Yuichi Yoshii

    Tokyo Medical University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

September 14, 2016

First Posted

September 21, 2016

Study Start

January 1, 2014

Primary Completion

May 1, 2024

Study Completion

May 1, 2025

Last Updated

April 27, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations