Noninvasive Perioperative Monitoring of Arterial Stiffness, Volume and Nutritional Status in Stable Renal Transplant Recipients

NCT02908139 | Unknown DMC

• 1 other identifier: PWV/KTx/2016/09
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Central blood pressure and pulse wave velocity were measured using a BR 102 Plus PWA device in perioperative time after kidney transplantation

Conditions

Arterial Calcification; Aortic Stiffness; High Blood Pressure; Kidney Transplantation

Outcome Measures

Primary Outcomes (1)

• Differences in pulse wave velocity [m/s] in short postoperative period.

  Assessment will be performed one day before kidney transplantation and two days after kidney transplantation

  3 days (one day before kidney transplantation and two days after kidney transplantation)

Secondary Outcomes (1)

• Differences in central aortic pressure [mmHg] in short postoperative period.

  3 days (one day before kidney transplantation and two days after kidney transplantation)

Study Arms (1)

Patients before kidney transplantation

The study included who had been admitted to the TransplantClinic before kidney transplantation

Device: BR-102 plus PWA; Device: Tanita MC780 MA S

Interventions

BR-102 plus PWA DEVICE

Monitoring of Arterial Stiffness and Central Aortic Pressure

Patients before kidney transplantation

Tanita MC780 MA S DEVICE

The device measured the size of total body water (TBW), Extra Cellular Water (ECW), Intra Cellular Water (ICW), fat mass (FM%), visceral fat%, fat free mass (FFM) and basal metabolic rate, (BMR) (kcal).

Patients before kidney transplantation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A total of 40 consecutive patients admitted to Transplant Centre to perform kidney transplantataion were included in this study.

You may qualify if:

• give voluntary consent to participate in the study
• no clinical cardiovascular disease during the 6 months preceding entry

You may not qualify if:

• not meet the above criteria

Sponsors & Collaborators

• Medical University of Warsaw: lead

Study Sites (1)

Medical University of Warsaw

Warsaw, Mazowian, 02-091, Poland

RECRUITING

Related Publications (3)

• Czyzewski L, Wyzgal J, Czyzewska E, Kurowski A, Sierdzinski J, Truszewski Z, Szarpak L. Assessment of Arterial Stiffness, Volume, and Nutritional Status in Stable Renal Transplant Recipients. Medicine (Baltimore). 2016 Feb;95(6):e2819. doi: 10.1097/MD.0000000000002819.

  PMID: 26871855 RESULT

• Czyzewski L, Sanko-Resmer J, Wyzgal J, Kurowski A. Comparative analysis of hypertension and its causes among renal replacement therapy patients. Ann Transplant. 2014 Nov 3;19:556-68. doi: 10.12659/AOT.891248.

  PMID: 25365639 RESULT

• Czyzewski L, Wyzgal J, Kolek A. Evaluation of selected risk factors of cardiovascular diseases among patients after kidney transplantation, with particular focus on the role of 24-hour automatic blood pressure measurement in the diagnosis of hypertension: an introductory report. Ann Transplant. 2014 Apr 28;19:188-98. doi: 10.12659/AOT.890189.

  PMID: 24770703 RESULT

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Lukasz Czyzewski, PhD

CONTACT

696457655; czyzewski_lukasz@wp.pl

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: September 12, 2016
• First Posted: September 20, 2016
• Study Start: September 1, 2016
• Primary Completion: September 1, 2017
• Study Completion: September 1, 2017
• Last Updated: June 15, 2017

Record last verified: 2017-06

Data Sharing

• IPD Sharing: Will not share

Locations

PL (1)