Effect of Strengthening the Hip Abductor in Patients With Knee Osteoarthritis: Randomized Controlled Trial

NCT02901964 | Completed DMC

• 1 other identifier: Doutorado
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

Osteoarthritis (OA) is a prevalent disease associated with significant morbidity and is one of the most common causes of joint pain. Characterized by their chronicity, slow and progressive evolution. The overall prevalence of symptomatic knee osteoarthritis is estimated at 3.8%, with peak prevalence in the population with an average age of 50 years. The main objectives of interventions in patients with knee OA are reduced pain and improved functional capacity and exercises are widely recommended. The literature shows a lack of clinical trials verifying the effect of strengthening the hip muscles in patients with knee osteoarthritis. Thus, the aim of this study is to assess the effect of strengthening the hip abductor muscles versus hip adductor muscles in patients with symptomatic OA of the knee.

Conditions

Osteoarthritis, Knee

Outcome Measures

Primary Outcomes (2)

• Numeric Pain Scale

  Pain was assessed by use of an 11-point Numeric Pain Scale, where 0 corresponded to no pain and 10 corresponded to worst imaginable pain.

  Six weeks

• Pain and Function subscale - Knee Injury and Osteoarthritis Outcome Score

  Pain and Function subscale - KOOS was assessed, where 0 corresponded to no pain and normal function and 100 corresponded to worst pain and function.

  Six weeks

Secondary Outcomes (7)

• Others subscales - Knee Injury and Osteoarthritis Outcome Score

  Six weeks

• 30 s Chair Stand Test

  Six weeks

• Timed Up & Go Test

  Six weeks

• Global Perceived Effect Scale

  Six weeks

• Numeric Pain Scale

  Six months

Study Arms (2)

Group Hip Abductor Exercise

EXPERIMENTAL

12 treatments sessions at 6 weeks: Heating, lower limb stretching, tibiofemoral and patellofemoral mobilization, strengthening the quadriceps, hamstrings, triceps sural and hip abductors.

Other: Hip Abductor Exercise

Group Hip Aductor Exercise

ACTIVE COMPARATOR

12 treatments sessions at 6 weeks: Heating, lower limb stretching, tibiofemoral and patellofemoral mobilization, strengthening the quadriceps, hamstrings, triceps sural and hip aductors.

Other: Hip Aductor Exercise

Interventions

Hip Abductor Exercise OTHER

12 treatments sessions at 6 weeks: Heating, lower limb stretching, tibiofemoral and patellofemoral mobilization, strengthening the quadriceps, hamstrings, triceps sural and hip abductors.

Group Hip Abductor Exercise

Hip Aductor Exercise OTHER

12 treatments sessions at 6 weeks: Heating, lower limb stretching, tibiofemoral and patellofemoral mobilization, strengthening the quadriceps, hamstrings, triceps sural and hip aductors.

Group Hip Aductor Exercise

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• OA knee radiograph grades 2 - 4 according to the Kellgren-Lawrence scale;
• Reporting knee pain with minimum intensity of 3 on Numerical Pain Scale;
• Complaints of pain and functional reduction in the last three months;
• Meet at least one of the American College of Rheumatology classification criteria;
• Deambulation independent;
• Absence of prostheses or orthoses
• Predominant pain in the medial aspect of the knee.

You may not qualify if:

• Contraindications for physical exercises evaluated by the Physical Activity Readiness Questionnaire (PAR-Q);
• Diabetes type I or decompensated;
• Hypertension decompensated;
• Cardiac pacemaker;
• Cancer History
• Neurological deficits (sensory or motor)
• Body mass index above 40 kg / m2
• Hip symptomatic osteoarthriti
• Orthopedic surgery of the lower limbs
• Systemic inflammatory disease
• Can not walk.

Sponsors & Collaborators

• Universidade Federal do Ceara: lead

Study Sites (1)

Federal University of Ceara

Fortaleza, Ceará, 60430-160, Brazil

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Gabriel Peixoto Leão Almeida, PhD student

  Federal University of Ceará (UFC), Brazil.

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 5, 2016
• First Posted: September 15, 2016
• Study Start: September 1, 2016
• Primary Completion: May 1, 2018
• Study Completion: November 1, 2018
• Last Updated: November 2, 2018

Record last verified: 2018-10

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)