Effect of Body Representation in Movement

NCT02898558 | Completed

• 1 other identifier: 702940
• Study Type: interventional
• Target: 25
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study explores the possible implications of the increase in perceived body size for rehabilitation of motor functions. In a recent study we have tested if motor abilities of patients with stroke improve wearing magnifying lenses, showing that a beneficial effect of magnifying lenses can be observed in some patients. In the present study, we will identify 12 patients from this cohort who demonstrated an improvement greater than 10% in one or two motor task when wearing magnifying glasses. These participants will be invited to take part in a clinical study in which they will undergo a training phase: subjects will wear magnifying lenses at home for 30 minutes daily for 14 days while completing a jigsaw puzzle; a log will be kept to document participation. Participants' performance on different motor tasks will be assessed before, immediately after and 1 month after the training session. Standardized measures of motor performance will include the the Action Research Arm test and the Rivermead Assessment of Somatosensory Performance (RASP). In addition, participants will undergo grip strength, finger tapping tasks and a reaching and grasping task. We expect the repeated use of magnifying lenses to generate an improvement of patients' performance across tasks and this effect to be persistent in time.

Conditions

Stroke

Outcome Measures

Primary Outcomes (1)

• Action Research Arm test

  19 item measure of motor control (i.e. (grasp, grip, pinch, and gross arm movement). Max score is 57

  Baseline, immediately after the training (two weeks) and after one month

Secondary Outcomes (4)

• Rivermead Assessment of Somatosensory Performance

  Baseline, immediately after the training (two weeks) and after one month

• Grip strength

  Baseline, immediately after the training (two weeks) and after one month

• Finger tapping

  Baseline, immediately after the training (two weeks) and after one month

• Reach and grasping

  Baseline, immediately after the training (two weeks) and after one month

Study Arms (1)

Magnification hand size

EXPERIMENTAL

magnifying lenses used for 30 minutes daily for 14 days while completing a jigsaw puzzle

Behavioral: Magnification hand size; Device: magnifying lenses

Interventions

Magnification hand size BEHAVIORAL

Participants will use magnifying lenses while completing a jigsaw puzzle for 30 min a day for 14 days.

Magnification hand size

magnifying lenses DEVICE

Magnification hand size

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients suffering from stroke who showed an improvement with magnifying lenses in our previous study.

You may not qualify if:

• Patients suffering from stroke who did not show an improvement with magnifying lenses in our previous study.

Sponsors & Collaborators

• University of Pennsylvania: lead
• Moss Rehabilitation Research Institute: collaborator

Related Publications (5)

• Kennett S, Taylor-Clarke M, Haggard P. Noninformative vision improves the spatial resolution of touch in humans. Curr Biol. 2001 Aug 7;11(15):1188-91. doi: 10.1016/s0960-9822(01)00327-x.

  PMID: 11516950 BACKGROUND

• Taylor-Clarke M, Jacobsen P, Haggard P. Keeping the world a constant size: object constancy in human touch. Nat Neurosci. 2004 Mar;7(3):219-20. doi: 10.1038/nn1199. Epub 2004 Feb 15.

  PMID: 14966526 BACKGROUND

• Mancini F, Longo MR, Kammers MP, Haggard P. Visual distortion of body size modulates pain perception. Psychol Sci. 2011 Mar;22(3):325-30. doi: 10.1177/0956797611398496. Epub 2011 Feb 8.

  PMID: 21303990 BACKGROUND

• Yozbatiran N, Der-Yeghiaian L, Cramer SC. A standardized approach to performing the action research arm test. Neurorehabil Neural Repair. 2008 Jan-Feb;22(1):78-90. doi: 10.1177/1545968307305353. Epub 2007 Aug 17.

  PMID: 17704352 BACKGROUND

• Winward CE, Halligan PW, Wade DT. The Rivermead Assessment of Somatosensory Performance (RASP): standardization and reliability data. Clin Rehabil. 2002 Aug;16(5):523-33. doi: 10.1191/0269215502cr522oa.

  PMID: 12194623 BACKGROUND

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Branch Coslett, MD

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

• Steven Jax, PhD

  MOSS S.p.A.

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 8, 2016
• First Posted: September 13, 2016
• Study Start: September 1, 2016
• Primary Completion: September 1, 2017
• Study Completion: September 1, 2017
• Last Updated: November 30, 2017

Record last verified: 2017-11

Data Sharing

• IPD Sharing: Will not share