Evaluating the Relationship Between Environmental Risk Factors in Housing Types and Chronic Respiratory Diseases in Ho Chi Minh City

NCT02898129 | Completed

• 1 other identifier: CHUB-CRD-Housing
• Study Type: interventional
• Target: 1,500
• Locations: 1 country
• Sites: 1

Brief Summary

The research question is "Are the different types of house in Ho Chi Minh city equally contributing to chronic respiratory diseases?". According to this question, a cross-sectional and explorative study was set up to explore the differences in the environmental characteristics and prevalence of chronic respiratory diseases among common housing types in Ho Chi Minh city. Preliminary work was performed in 100 houses (20 houses per type, included tube houses, rental houses, rural houses, slum and apartment) from November 2013 to June 2015. It included measures by environmental devices, questionnaires and indoor activities diaries. This study will aim to collect information about the prevalence of chronic respiratory diseases (CRDs) inside those house types to understand more about role of house types in developing CRDs. The objective is:

1. 1.to evaluate the relationships between the type of house and lung function of inhabitants in each housing type.
2. 2.to evaluate the effects of environmental risk factors in each house type on prevalence of CRDs

Conditions

Chronic Respiratory Diseases

Keywords

chronic respiratory diseases; housing; lung function test

Outcome Measures

Primary Outcomes (7)

• FEV1/FVC

  Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes are performed during the same test. FEV1: forced expiratory volume in one second. FVC: Forced vital capacity.

  5 minutes

• FVC

  Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes are performed during the same test.FVC: Forced vital capacity.

  5 minutes

• VC

  Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes performed during the same test. VC: Vital capacity

  5 minutes

• FEF 25-75%

  Basic lung function test, without broncho dilatation (micro-spirometer).All lung function related outcomes are performed during the same test. FEF: Forced expiratory flow

  5 minutes

• Socio-demographic status

  Socio-demographic data, assessed by a home made questionnaire

  around 10 minutes

• Health status

  Health status (symptomatology) data, assessed by a home made questionnaire

  around 10 minutes

• Indoor air exposure time

  Indoor air exposure (time spent indoor within housing types, with associated air characteristics) data, assessed by a home made questionnaire

  around 10 minutes

Study Arms (4)

Tube houses

EXPERIMENTAL

Tube Houses. Group of 75-100 houses, with 4 inhabitants per house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.

Other: Questionnaire; Device: Lung function test

Apartment

EXPERIMENTAL

Apartments. Group of 75-100 apartments, with 4 inhabitants per apartment. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.

Other: Questionnaire; Device: Lung function test

Rental Houses

EXPERIMENTAL

Rental Houses. Group of 150-200 rental houses, with 2 inhabitants per rental house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.

Other: Questionnaire; Device: Lung function test

Rural houses

EXPERIMENTAL

Rural Houses. Group of 40-60 rural houses, with 5 inhabitant per rural house. Expected number of participants: 200-300. Predicted number of non-smoker chronic respiratory disease of 12-18.

Other: Questionnaire; Device: Lung function test

Interventions

Questionnaire OTHER

Apartment; Rental Houses; Rural houses; Tube houses

Lung function test DEVICE

Basic lung function test performed with a micro-spirometer, without broncho dilatator

Apartment; Rental Houses; Rural houses; Tube houses

Eligibility Criteria

• Age: 10 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Everybody

You may not qualify if:

• Not able to answer the questionnaire or give informed consent
• Have a contra-indication for lung function test (acute myocardial infarction less that 1 month ago, pain related to spirometry, dementia/confused)

Sponsors & Collaborators

• Brugmann University Hospital: lead

Study Sites (1)

Pham Ngoc Thach University of medicine

Ho Chi Minh City, 7000, Vietnam

Location

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MeSH Terms

Interventions

Surveys and Questionnaires; Respiratory Function Tests

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health; Diagnostic Techniques, Respiratory System; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of clinic

Study Record Dates

• First Submitted: September 8, 2016
• First Posted: September 13, 2016
• Study Start: September 1, 2016
• Primary Completion: July 1, 2017
• Study Completion: July 1, 2017
• Last Updated: August 4, 2017

Record last verified: 2017-08

Locations

VN (1)