NCT02892383

Brief Summary

The aim of the project is to improve quality of life for multiple myeloma patients in the future.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
681

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2017

Longer than P75 for all trials

Geographic Reach
1 country

10 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 14, 2016

Completed
3 months until next milestone

First Posted

Study publicly available on registry

September 8, 2016

Completed
6 months until next milestone

Study Start

First participant enrolled

February 27, 2017

Completed
6.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2023

Completed
Last Updated

September 23, 2024

Status Verified

September 1, 2024

Enrollment Period

6.8 years

First QC Date

June 14, 2016

Last Update Submit

September 19, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • A longitudinal description of quality of life (QoL) using patient-reported outcomes measurement (PROM) for the general population of multiple myeloma patients.

    a. Description of changes in QoL over time

    24 months

Secondary Outcomes (3)

  • Description of changes in QoL over time, based on PROM for the general population of multiple myeloma patients.

    24 months

  • Description of the impact of peripheral neuropathy on QoL in the general population of multiple myeloma patients over time, based on PROM.

    24 months

  • Description of the impact of recalibration response shift for interpretation of data from longitudinal QoL studies using PROM for QoL measurement in the general population of previously untreated multiple myeloma patients.

    9 months

Eligibility Criteria

Age18 Years - 110 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Danish multiple myeloma patients

You may qualify if:

  • Previously untreated or relapsed multiple myeloma patients AND
  • Treatment demanding multiple myeloma disease

You may not qualify if:

  • Inability to understand the Danish language or
  • Psychic or mental illness that prevents the patient from answering the questions in the questionnaires.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

Sygehus Sønderjylland

Aabenraa, Denmark

Location

Aalborg University Hospital

Aalborg, Denmark

Location

Aarhus University Hospital

Aarhus, Denmark

Location

Rigshospitalet

Copenhagen, Denmark

Location

Sydvestjysk Sygehus

Esbjerg, Denmark

Location

Herlev Hospital

Herlev, Denmark

Location

Hospitalsenheden Vest

Holstebro, Denmark

Location

Odense University Hospital

Odense, Denmark

Location

Sjællands Universitetshospital

Roskilde, Denmark

Location

Vejle Sygehus

Vejle, Denmark

Location

Related Publications (1)

  • Engelhardt M, Ihorst G, Singh M, Rieth A, Saba G, Pellan M, Lebioda A. Real-World Evaluation of Health-Related Quality of Life in Patients With Multiple Myeloma From Germany. Clin Lymphoma Myeloma Leuk. 2021 Feb;21(2):e160-e175. doi: 10.1016/j.clml.2020.10.002. Epub 2020 Oct 24.

MeSH Terms

Conditions

Multiple Myeloma

Condition Hierarchy (Ancestors)

Neoplasms, Plasma CellNeoplasms by Histologic TypeNeoplasmsHemostatic DisordersVascular DiseasesCardiovascular DiseasesParaproteinemiasBlood Protein DisordersHematologic DiseasesHemic and Lymphatic DiseasesHemorrhagic DisordersLymphoproliferative DisordersImmunoproliferative DisordersImmune System Diseases

Study Officials

  • Lene Kongsgaard Nielsen, MD

    Quality of Life Research Centre, Haematological Department, Odense Univsersity Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Specialist in Haematology

Study Record Dates

First Submitted

June 14, 2016

First Posted

September 8, 2016

Study Start

February 27, 2017

Primary Completion

November 30, 2023

Study Completion

November 30, 2023

Last Updated

September 23, 2024

Record last verified: 2024-09

Data Sharing

IPD Sharing
Will share

The cohort will be used as historical controls in clinical intervention trials

Locations