NCT02891330

Brief Summary

The postprandial dumping syndrome is a frequent consequence of Roux-en-Y Gastric ByPass due to the rapid emptying of the stomach remnant in to the intestinal lumen. Dumping-related symptoms occur very early after eating (within 30 minutes), are not associated with concurrent hypoglycemia, and are most prominent in the early postoperative period. This syndrome very debilitating for the patient can be improved by dietary and nutritional recommendations. We hypothesize that a personalized approach based on dietary and nutritional recommendations conducted by a nurse would likely to decrease the frequency of dumping syndrome and improve the postoperative quality of life of patients in the early postoperative period.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
135

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 1, 2016

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 7, 2016

Completed
6 months until next milestone

Study Start

First participant enrolled

March 2, 2017

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 18, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 18, 2020

Completed
Last Updated

April 21, 2021

Status Verified

April 1, 2021

Enrollment Period

3.8 years

First QC Date

September 1, 2016

Last Update Submit

April 20, 2021

Conditions

Keywords

Roux-en-Y Gastric ByPass

Outcome Measures

Primary Outcomes (1)

  • The frequency of dumping syndrome

    The frequency of dumping syndrome at 3 months will be compared between the two groups.

    3 months

Secondary Outcomes (4)

  • Change in Body Mass Index

    3 months

  • Frequence of Adverse Events after surgery

    at 1 and 3 months

  • Quality of Life-Lite questionnaire

    3 months

  • Personal Effectiveness Assessment questionnaire (SEPOB)

    3 months

Study Arms (2)

Dietary and nutritional recommendations

EXPERIMENTAL

Postoperative personalized approach based on dietary and nutritional recommendations conducted by a nurse

Behavioral: Dietary and nutritional recommendations conducted by a nurse

Standard of care

NO INTERVENTION

Postoperative standard of care

Interventions

Supplementary dietary and nutritional education

Dietary and nutritional recommendations

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body Mass Index ≥40 kg / m2 or ≥35 kg / m2 in the presence of comorbidities related to obesity
  • Indication to Roux-en-Y Gastric ByPass

You may not qualify if:

  • Contraindication to Roux-en-Y Gastric ByPass
  • Refusal to sign the consent form
  • Patient not affiliated to a social security system
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

CH ARRAS

Arras, France

Location

Ch Boulogne-Sur-Mer

Boulogne-sur-Mer, 62321, France

Location

Hôpital Claude Huriez, CHRU

Lille, France

Location

Ch de Valenciennes

Valenciennes, France

Location

MeSH Terms

Conditions

Dumping Syndrome

Interventions

Diet

Condition Hierarchy (Ancestors)

Postgastrectomy SyndromesStomach DiseasesGastrointestinal DiseasesDigestive System DiseasesPostoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Nutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological Phenomena

Study Officials

  • Hélène VERKINDT, MD

    University Hospital, Lille

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 1, 2016

First Posted

September 7, 2016

Study Start

March 2, 2017

Primary Completion

December 18, 2020

Study Completion

December 18, 2020

Last Updated

April 21, 2021

Record last verified: 2021-04

Data Sharing

IPD Sharing
Will not share

Locations