NCT02889471

Brief Summary

110 patients with common bile duct (CBD) stones and had one or more anther preoperative predictors for high risk for difficult cholecystectomy admitted to departement of surgery of Minia university hospital for ERCP then laparoscopic cholecystectomy (LC). the patient divided into 2 equal group. in group 1, nasobiliary (NB) catheter was inserted during ERCP after CBD clearance. In group 2, only CBD clearance was done. In all patients LC was done within the same week of ERCP. Tans-nasobiliary Intraoperative cholangiography was done and methylene blue injected at the end of the procedure to detected any leak in NB group

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2015

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

August 30, 2016

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 5, 2016

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2017

Completed
Last Updated

February 12, 2018

Status Verified

February 1, 2018

Enrollment Period

2.3 years

First QC Date

August 30, 2016

Last Update Submit

February 9, 2018

Conditions

Outcome Measures

Primary Outcomes (2)

  • biliary injury

    the incidence of biliary injury complicating cholecystectomy either discovered intraoperative or postoperative

    2 weeks

  • conversion to open

    incidence of conversion to open

    6 hours

Secondary Outcomes (3)

  • operative time

    6 hours

  • hospital stay

    one month

  • mortality

    one month

Study Arms (2)

ERCP with nasobiliary catheter

EXPERIMENTAL
Procedure: ERCP with NB

ERCP only

ACTIVE COMPARATOR
Procedure: ERCP alone

Interventions

ERCP with NBPROCEDURE

ERCP with NB catheter for introperative tans-nasobiliary cholangiography

ERCP with nasobiliary catheter
ERCP alonePROCEDURE

ERCP alone followed with standard laparoscopic cholecystectomy

ERCP only

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients with GB stone complicated with CBD stones
  • accept to share in the study
  • the presence of one or more preoperative predictors for high risk for difficult cholecystectomy
  • patient fit for LC

You may not qualify if:

  • patients\< 18 and \>80
  • unfit for surgery
  • didn't accept to share in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Minya university hospital

Minya, 61511, Egypt

Location

MeSH Terms

Interventions

Cholangiopancreatography, Endoscopic Retrograde

Intervention Hierarchy (Ancestors)

CholangiographyRadiography, AbdominalRadiographyDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisDiagnostic Techniques, Digestive SystemEndoscopy, Digestive SystemEndoscopyDiagnostic Techniques, SurgicalDigestive System Surgical ProceduresSurgical Procedures, OperativeMinimally Invasive Surgical Procedures

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, Lecturer & consultant of general surgery, Department of surgery, Minia university hospital, Egypt

Study Record Dates

First Submitted

August 30, 2016

First Posted

September 5, 2016

Study Start

April 1, 2015

Primary Completion

August 1, 2017

Study Completion

August 1, 2017

Last Updated

February 12, 2018

Record last verified: 2018-02

Locations