Correlation of Arterial and Venous Lactate and Base Deficit Values

NCT02888431 | Completed

• 1 other identifier: IRB15-00793
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine the correlation between pH, base deficit, and lactate values when comparing venous and arterial blood samples in the pediatric population.

Conditions

Arterial Access; Peripheral Access; Central Venous Catheter

Keywords

pH; base deficit; lactate values; venous blood samples; arterial blood samples

Outcome Measures

Primary Outcomes (3)

• lactate blood value

  blood will be drawn from peripheral venous line, arterial line, and/or central venous line then the lactate value will be assessed by using a bedside point-of-care device, called i-stat.

  During surgery- approximately 15-20 minutes after induction in the operating room (OR)

• base deficit blood value

  blood will be drawn from peripheral venous line, arterial line, and/or central venous line then the base deficit blood value will be assessed by using a bedside point-of-care device, called i-stat.

  During surgery- approximately 15-20 minutes after induction in the operating room (OR)

• pH blood value

  blood will be drawn from peripheral venous line, arterial line, and/or central venous line then pH blood value will be assessed by using a bedside point-of-care device, called i-stat.

  During surgery- approximately 15-20 minutes after induction in the operating room (OR)

Study Arms (2)

Arterial blood sample

0.5 mL blood sample from arterial line which is clinically indicated

Device: bedside point-of-care device

peripheral venous blood sample

0.5 mL blood sample drawn simultaneously with arterial sample from clinically indicated peripheral line

Device: bedside point-of-care device

Interventions

bedside point-of-care device DEVICE

A bedside point-of-care device is routinely used in the operating room to measure lactate, base deficit, and pH.

Arterial blood sample; peripheral venous blood sample

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients requiring arterial access and peripheral access. Additionally, patients with a central venous catheter would be included.

You may qualify if:

• Patients requiring arterial access and peripheral access. Additionally, patients with a central venous catheter would be included.

You may not qualify if:

• Patients who not require arterial access.

Sponsors & Collaborators

• Joseph D. Tobias: lead

Study Sites (1)

Nationwide Children's Hospital

Columbus, Ohio, 43205, United States

Location

Study Officials

• Joseph Tobias

  Nationwide Children's Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Chairman, Professor of Anesthesiology

Study Record Dates

• First Submitted: August 17, 2016
• First Posted: September 5, 2016
• Study Start: September 1, 2015
• Primary Completion: December 1, 2016
• Study Completion: December 1, 2016
• Last Updated: January 31, 2017

Record last verified: 2017-01

Locations

US (1)