NCT02886078

Brief Summary

The primary objective is to investigate the active extension six months after implantation of the CapFlex-PIP© arthroplasty, comparing the dorsal with the volar approach. This is a randomized controlled trial including 70 patients with PIP OA indicated for CapFlex arthroplasty.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2016

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 23, 2016

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 1, 2016

Completed
1 month until next milestone

Study Start

First participant enrolled

October 1, 2016

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

June 16, 2017

Status Verified

June 1, 2017

Enrollment Period

8 months

First QC Date

August 23, 2016

Last Update Submit

June 15, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Active extension of the PIP joint measured with a goniometer

    6 months after surgery

Secondary Outcomes (1)

  • Subjective function using the Brief Michigan Hand Questionnaire (briefMHQ)

    6 months after surgery

Study Arms (2)

Dorsal approach CapFlex arthroplasty

EXPERIMENTAL

Arthroplasty of the PIP joint with the CapFlex implant. Surgery will be done with the dorsal approach.

Procedure: Dorsal approach CapFlex arthroplasty

Volar approach CapFlex arthroplasty

ACTIVE COMPARATOR

Arthroplasty of the PIP joint with the CapFlex implant. Surgery will be done with the volar approach.

Procedure: Volar approach CapFlex arthroplasty

Interventions

Arthroplasty of the PIP joint with the CapFlex implant. Surgery will be done with the dorsal approach.

Dorsal approach CapFlex arthroplasty

Arthroplasty of the PIP joint with the CapFlex implant. Surgery will be done with the volar approach.

Volar approach CapFlex arthroplasty

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Indication for CapFlex-PIP© arthroplasty
  • Patient aged 18 years and over
  • Informed Consent as documented by signature

You may not qualify if:

  • Revision surgery
  • CapFlex-PIP© arthroplasty at the thumb IP joint
  • Major surgery at the same finger (e.g. DIP arthrodesis)
  • Ulnar/radial deviation of the PIP joint \> 15°
  • Patients in which a reconstruction of the collateral ligaments has to be performed
  • General medical contraindication to surgery
  • German language barrier to complete the questionnaires
  • Any disease process that would preclude accurate evaluation (e.g. neuromuscular, psychiatric or metabolic disorder)
  • Pregnancy
  • Surgery not planned by Dr. Herren, Dr. Schindele or Dr. Bodmer
  • Legal incompetence

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Schulthess Klinik

Zurich, 8008, Switzerland

Location

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Dr. phil.

Study Record Dates

First Submitted

August 23, 2016

First Posted

September 1, 2016

Study Start

October 1, 2016

Primary Completion

June 1, 2017

Study Completion

June 1, 2017

Last Updated

June 16, 2017

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share

No plan to share data

Locations