Effects of Inverted Vision on Pointing and Grasping in Parabolic Flight

NCT02885844 | Unknown

• 1 other identifier: 2014-A00813-44
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

Parabolic flight is the only ground-based condition in which weightlessness (0G) can be created long enough for safely testing changes in human perception and behavior. In addition to the 0G period, parabolic flight generates equal duration periods of 1.8G, which present another unique opportunity to test the same responses to hypergravity and back to 1G. Spatial orientation perception is a critical subsystem that is used by the central nervous system in the control of vehicles and other complex systems in a high-level integrative function. Evidence from space flight research demonstrates that spatial orientation is altered by the transitions in gravito-inertial force levels (Clément 2011; Clément \& Reschke 2008), transitions corresponding to mission phases particularly critical for crew safety and mission success. Accurate perception of self-in-space motion and self-motion relative to other objects is critical for successful operations that involve motor control e.g. doing an extra-vehicule activity or piloting the spacecraft. To date, there is only limited operational evidence that these alterations cause functional impacts on mission-critical operations and control capabilities. Immediately after space flight, most crewmembers have reported some degree of disorientation/perceptual illusion, often accompanied by nausea (or other symptoms of motion sickness), and frequently manifested by lack of coordination, particularly during locomotion The hypothesis is that alteration in sensorimotor performance induced by inverted vision is gravity depend: maximum alteration during hypergravity, intermediary alteration during normal gravity, minimal alteration during weightlessness.

Conditions

Pointing Task; Gasping Task

Outcome Measures

Primary Outcomes (1)

• Response time

  the time between when the target or shape appears and the subject lifts their finger off of the screen

  During flight

Secondary Outcomes (2)

• Task duration

  During flight

• Accuracy

  During flight

Study Arms (2)

INVERTED VISION

EXPERIMENTAL

inverted vision (upside down) using commercial off-the-shelf inverting prism goggles

Procedure: INVERTED VISION

NORMAL VISION

ACTIVE COMPARATOR

During normal vision trials, subject's field of view will be restricted by goggles without lenses (see below) in order to be equivalent to the inverted vision one.

Procedure: NORMAL VISON

Interventions

INVERTED VISION PROCEDURE

The tasks will be performed either with normal or inverted vision (upside down) using commercial off-the-shelf inverting prism goggles

INVERTED VISION

NORMAL VISON PROCEDURE

subject's field of view will be restricted by goggles without lenses in order to be equivalent to the inverted vision one.

NORMAL VISION

Eligibility Criteria

• Age: 21 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Subjects will be staff member of the team or of other teams participating in the parabolic flight campaign
• Healthy volunteers (men or women)
• Aged from 21 to 65
• Affiliated to a Social Security system and, for non-French resident, holding a European Health Insurance Card (EHIC)
• Who accepted to take part in the study
• Who have given their written stated consent
• Who has passed a medical examination similar to a standard aviation medical examination for private pilot aptitude (JAR FCL3 Class 2 medical examination). There will be no additional test performed for subject selection.

You may not qualify if:

• Person with medical history of oculomotor disorders
• Person with medical history of vestibular disorders
• Pregnant women

Sponsors & Collaborators

• University Hospital, Caen: lead
• International Space University: collaborator

Study Sites (1)

CHU Caen

Caen, 14000, France

RECRUITING

Study Officials

• Clément GC Gilles

  International Space University

  STUDY DIRECTOR

Central Study Contacts

Pierre DP Denise, PhD

CONTACT

02.31.06.81.32; pierre.denise@unicaen.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 8, 2016
• First Posted: September 1, 2016
• Study Start: September 1, 2014
• Primary Completion: September 1, 2017
• Study Completion: October 1, 2017
• Last Updated: September 1, 2016

Record last verified: 2016-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)