Daily Ginger Drinking and Platelet Function

NCT02882776 | Completed DMC

• 1 other identifier: RC12/080
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to examine the effect of ginger beverage consumption on platelets activity in apparently healthy Saudi adult volunteers. As for the Saudi population, consumption of powdered ginger dissolved in hot water is a common practice. Accordingly, in this study, it is tempting to speculate the effect of this form of ginger consumption, given in separate time points per day, on platelet aggregation profile by using platelet aggregation analogues. If positive results were obtained, the herb could provide natural protection against the development of platelet aggregation complications and could be a potential alternative to aspirin, used for improving blood circulation and hematological pathophysiologies in diseased individuals.

Conditions

Platelets Dysfunction; Hematological Diseases

Outcome Measures

Primary Outcomes (1)

• The effect of ginger beverage consumption on platelets activity will be examined in apparently healthy, Saudi adult volunteers.

  1 year

Secondary Outcomes (4)

• The demographic characteristics of the sample under study will be identified.

  1 year

• Any change in platelet morphology before and after ginger consumption will be studied

  1 year

• Platelets' count before and after ginger consumption will be compared.

  1 year

• Any change in platelets function after ginger consumption via addition of aggregation analogues will be studied.

  1 year

Study Arms (2)

Ginger drink once daily

OTHER

this group will receive ginger drink made by dissolving 4g ginger powder in plain water once a day for continuous 5 days.

Dietary Supplement: Ginger drink

Ginger drink twice daily

OTHER

this group will receive ginger drink made by dissolving 4g ginger powder in plain water twice a day for continuous 5 days.

Dietary Supplement: Ginger drink

Interventions

Ginger drink DIETARY_SUPPLEMENT

Ginger powder dissolved in water

Ginger drink once daily; Ginger drink twice daily

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Apparently healthy Saudi volunteers of either sex
• Age group = 18-60 years.

You may not qualify if:

• History of organ abnormalities or concomitant illnesses.
• Abnormal platelets count or function.
• Individuals with bleeding disorder as Von Willebrand Disorder or Hemophilia.
• Known allergy to ginger.
• Concurrent warfarin ingestion.
• History of ingestion of asprin,clopidogrel, nifedipine, non-steroid anti-inflammatory drugs (NSAIDs) or ethanol within the past two week.
• Any volunteer ingests ethanol, aspirin, clopidogrel, wine, beer and contraceptive pills during the study duration will be excluded from the study.
• pregnant \& lactating women.
• Individuals on herbal treatment.
• Active G.I ulcers/ recently diagnosed G.I ulcers within one month

Sponsors & Collaborators

• King Abdullah International Medical Research Center: lead

Study Sites (1)

King Abdulaziz Medical City - National Guard Hospital

Riyadh, Central, 11426, Saudi Arabia

Location

MeSH Terms

Conditions

Hematologic Diseases

Condition Hierarchy (Ancestors)

Hemic and Lymphatic Diseases

Study Officials

• Dr. Askar S. Alaskar, MD,FACP,FRCP

  King Abdullah Medical research Center - King Abdulaziz Medical City - Riyadh

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 10, 2016
• First Posted: August 30, 2016
• Study Start: December 1, 2013
• Primary Completion: July 1, 2016
• Study Completion: July 1, 2016
• Last Updated: August 30, 2016

Record last verified: 2016-08

Data Sharing

• IPD Sharing: Will share

Locations

SA (1)