Prehabilitation Physical Activity in Persons With Osteoarthritis

NCT02881463 | Completed Phase 4 DMC

• 1 other identifier: 218/T-16
• Study Type: interventional
• Target: 45
• Locations: 0 countries
• Sites: N/A

Brief Summary

Knee joint osteoarthritis (OA) reduces functional mobility and performance of daily tasks such as rising from a chair. Therefore interventions aimed at improving muscle strength and sit-to-stand task performance are very important for these patients. The effect of exercise programs, including home exercise programs (HEP), on muscle strength, joint pain and function is well known and widely researched, yet not many studies have investigated the effect of an HEP on electromyographic activity (EMG) of muscles when performing everyday tasks, such as rising from and sitting on a chair. The aim of this study was to investigate effect of prehabilitation in women with severe knee joint OA scheduled for knee joint arthroplasty (TKA).

Conditions

Osteoarthritis

Outcome Measures

Primary Outcomes (1)

• Muscle electromyographic (EMG) activity

  Electromyographic (EMG) activity of thigh muscles during gait and sit to stand task (amplitude, mV)

  up to 12 months

Secondary Outcomes (7)

• Knee joint pain intensity

  up to 12 months

• Knee joint function

  up to 12 months

• Sit to Stand test

  up to 12 months

• Mobility test

  up to 12 months

• Leg muscles strength

  up to 12 months

Study Arms (1)

Home Exercise Program

EXPERIMENTAL

8- week therapeutical exercise program performing at home for women with knee joint osteoarthritis

Other: therapeutical exercises

Interventions

therapeutical exercises OTHER

Participants of experimental group performs daily an 8-week home therapeutical exercise program. Exercises are periodized by weeks (1-8 weeks). The aim of program is the leg muscle strengthening using an elastic band (Thera-Band, System of Progressive Exercise, USA), body balance training, and leg muscle stretching.

Home Exercise Program

Eligibility Criteria

• Age: 50 Years - 70 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• For OA patients: patients with severe knee joint OA undergoing unilateral total knee arthroplasty (TKA)
• for controls: pain of joints more than 20/100 mm by VAS

You may not qualify if:

• For both groups:
• previous total joint arthroplasty of lower limbs
• other musculoskeletal, neurological and cardiovascular diseases
• any diseases affecting balance and coordination.

Sponsors & Collaborators

• University of Tartu: lead

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Helena Gapeyeva, MD, PhD

  University of Tartu, Faculty of Medicine, Estonia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Fellow, Md, PhD

Study Record Dates

• First Submitted: June 16, 2016
• First Posted: August 29, 2016
• Study Start: January 1, 2013
• Primary Completion: June 1, 2016
• Study Completion: June 1, 2016
• Last Updated: September 13, 2016

Record last verified: 2016-09