NCT02879045

Brief Summary

The effect of elasticity Belly® oil and Clarins® Tonic Body Treatment Oil in prevention of striae gravidarum: A randomized controlled clinical trial.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for phase_2

Timeline
Completed

Started Aug 2016

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2016

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

August 20, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 25, 2016

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2017

Completed
Last Updated

May 5, 2017

Status Verified

May 1, 2017

Enrollment Period

1 year

First QC Date

August 20, 2016

Last Update Submit

May 4, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • occurrence and severity of striae gravidarum

    volunteer's abdomen skin are divided into two parts through medioventral line, half of the abdomen skin will receive the elasticity Belly® oil , and the other side will use the Clarins® Tonic Body Treatment Oil. Volunteers apply these two kinds of oil daily until birth. We'll take abdomen pictures before and after interventions, and the occurrence of striae on abdominal skin and its severity will be evaluated as our primary end point of the study.

    second trimester to term birth

Study Arms (1)

elasticity Belly® oil

EXPERIMENTAL

Volunteer's abdomen skin are divided two parts through medioventral line, half of the abdomen skin will apply the elasticity Belly® oil

Other: Elasticity Belly® oil

Interventions

We will enroll about 50 Nulliparous women randomly, who are in their second trimester of pregnancy. We divide each of the volunteer's abdomen skin into two parts through medioventral line, one of the abdomen skin will receive the elasticity Belly® oil to prevent striae gravidarum, and the other side will use the Clarins® oil. Volunteers apply these two kinds of oil daily until birth. We'll take abdomen pictures before and after interventions, and the occurrence of striae on abdominal skin and its severity will be evaluated as our primary end point of the study.

elasticity Belly® oil

Eligibility Criteria

Age20 Years - 35 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • nulliparous females
  • gestational age of 14-20 weeks
  • to 35 years old
  • body mass index (BMI) from 18.5 to 25
  • Clear consciousness, intelligence is normal,stable vital signs
  • Voluntary participation, and sign the informed consent

You may not qualify if:

  • allergy to skin care products
  • twin pregnancies or polypregnancies
  • polyhydramnios
  • miscarriages
  • development of a skin disease
  • corticosteroid usage
  • application of any other cream on the abdominal skin
  • did not received allocated intervention
  • drop out or lost to follow-up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shanghai Changning Maternity & Infant Health Hospital

Shanghai, Shanghai Municipality, 200051, China

RECRUITING

Study Officials

  • Shating Lei, PhD

    Tongji University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Dong Zhao, M.D.

CONTACT

Shating Lei, PhD

CONTACT

Study Design

Study Type
interventional
Phase
phase 2
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
associal professor

Study Record Dates

First Submitted

August 20, 2016

First Posted

August 25, 2016

Study Start

August 1, 2016

Primary Completion

August 1, 2017

Study Completion

August 1, 2017

Last Updated

May 5, 2017

Record last verified: 2017-05

Data Sharing

IPD Sharing
Will not share

Locations