Effect Aerobic Training on Women With Breast Cancer After Chemotherapy

NCT02876627 | Completed Phase 1

• 1 other identifier: 201527904IR
• Study Type: interventional
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

Introduction: The purpose of this study was to determine the effect of twelve weeks of aerobic exercise program on erythrocyte levels in women with breast cancer after chemotherapy. Methods: Thirty women with breast cancer after chemotherapy of Sydalshhda hospital (aged between 47-65 years) volunteered for this study, and then randomly selected an exercise (n = 15) and control (n = 15) groups. Exercise group completed a twelve-week aerobic exercise training program consisted of three sessions per week, each session lasting 30 to 60 minutes 50 to 75 percent of their maximum heart rate reserve, while the control group were followed. Blood samples including red blood cell counts (RBC), hematocrit (HCT), hemoglobin (HB), peak oxygen consumption before and after 12 weeks of aerobic exercise were measured. For analysis of data, repeated-measures analysis of variance (ANOVA) was used.

Conditions

Cancer; Exercise; Hemoglobins

Outcome Measures

Primary Outcomes (1)

• effect of exercise on CBC parameters (measured by ELISA methods)

  up to 12 weeks

Secondary Outcomes (1)

• effect of exercise on peak oxygen consumption, measured by vo2 max test

  up to 12 weeks

Study Arms (1)

breast cancer

EXPERIMENTAL

Effect of exercise training on breast cancer patient

Behavioral: Exercise training

Interventions

Exercise training BEHAVIORAL

twelve-week aerobic exercise training program consisted of three sessions per week, each session lasting 30 to 60 minutes 50 to 75 percent of their maximum heart rate reserve

breast cancer

Eligibility Criteria

• Age: 47 Years - 65 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• women with breast cancer , who can do a physical, physiological and psychological test; and did not have exercise limitations due to neuromuscular and/or musculoskeletal disease; did not have any health problems that prevented maximum effort on the treadmill test.

You may not qualify if:

• women under erythropoietin treatments, uncontrolled cardiovascular or pulmonary diseases, uncontrolled arrhythmias, orthopedic conditions that would limit exercise participation, refusal for randomization, or participation in aerobic exercise training within 3 months before beginning the study.

Sponsors & Collaborators

• University of Isfahan: lead

MeSH Terms

Conditions

Neoplasms; Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 15, 2016
• First Posted: August 24, 2016
• Study Start: February 1, 2015
• Primary Completion: June 1, 2015
• Study Completion: April 1, 2016
• Last Updated: August 24, 2016

Record last verified: 2016-08