NCT02874352

Brief Summary

This study will inform the feasibility of the High Resolution Impedance Manometry (HRIM) system combined with Automated Impedance Manometry (AIM) analysis as a screening tool for dysphagia and aspiration for the intensive care population with tracheostomy. This pilot study aims to determine the incidence of dysphagia and aspiration risk in intensive care patients with tracheostomy and the investigators hypothesise that the incidence of dysphagia in intensive care patients with tracheostomy will be higher than in an age matched population.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2016

Typical duration for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 17, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 22, 2016

Completed
1 month until next milestone

Study Start

First participant enrolled

October 1, 2016

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2018

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2018

Completed
Last Updated

August 23, 2016

Status Verified

August 1, 2016

Enrollment Period

1.6 years

First QC Date

August 17, 2016

Last Update Submit

August 22, 2016

Conditions

Keywords

intensive caretracheostomy

Outcome Measures

Primary Outcomes (1)

  • Pressure Flow Measurements

    Pressure Flow measurements generated by HRIM registrations and analysed by AIM analysis

    1 hour

Secondary Outcomes (2)

  • Sydney Swallow Questionaire (SSQ)

    1 hour

  • Functional Oral Intake Scale (FOIS)

    1 hour

Study Arms (2)

intensive care patients

OTHER

intensive care patients with tracheostomy/ high resolution impedance manometry with Automated Impedance Manometry analysis

Device: high resolution impedance manometry with Automated Impedance Manometry analysis

healthy volunteers

OTHER

control group with healthy volunteers/ high resolution impedance manometry with Automated Impedance Manometry analysis

Device: high resolution impedance manometry with Automated Impedance Manometry analysis

Interventions

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Intensive care patient with tracheostomy ( applies only to patients)
  • Age \> 18 years
  • Ability to sit upright and to swallow on command as well as to swallow thin liquids
  • Informed and signed consent

You may not qualify if:

  • Pre-existing dysphagia
  • History of upper gastrointestinal surgery
  • Current medication known to affect esophageal motility
  • Pregnancy
  • Severe coagulopathy
  • Allergy to local anaesthetics

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Deglutition Disorders

Condition Hierarchy (Ancestors)

Esophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesPharyngeal DiseasesOtorhinolaryngologic Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 17, 2016

First Posted

August 22, 2016

Study Start

October 1, 2016

Primary Completion

May 1, 2018

Study Completion

September 1, 2018

Last Updated

August 23, 2016

Record last verified: 2016-08

Data Sharing

IPD Sharing
Will not share