The Role of Emotions and Regulatory Focus in Decision Making That Involves Risk Tradeoffs

NCT02874053 | Withdrawn

• 2 other identifiers: 99991616116-C-N161
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

Background: People with cancer often have to make complex decisions about their treatment. For some of these decisions, they have to weigh the benefits of a treatment against its side effects. They may have to think about its potential to increase the risk of another disease. One example is hormone replacement therapy. That reduces a woman s risk of getting colorectal cancer, but it raises her risk of getting breast cancer. Researchers want to learn more about how people make tradeoff decisions like these. Objective: To learn about how people respond to information about hypothetical health and medical treatment options. Eligibility: Adults ages 18 70. Design: Participants will have one 30-minute visit. Participants will complete a series of short questionnaires. These will be about their beliefs and values. Some may be about cancer and heart disease risk. Participants ages 18 to 29 will answer questions about sexual health. Participants will write a paragraph or two about a room in their house or about a life event. Participants will read a series of stories. These will describe different hypothetical health treatments. The stories describe a pill that lowers the risk of one health condition, but raises the risk for another. After each story, participants will note how willing they are to take the pill. Participants will answer questions about the information that they got. They will also answer questions about their health, beliefs, and opinions. Participants will do 2 attention tasks computer.

Conditions

Cancer

Keywords

Risk Perceptions; Medical Tradeoffs; Regulatory Focus; Integral Affect

Outcome Measures

Primary Outcomes (1)

• willingness to take hypothetical pill

  self-reported behavioral willingness

  at baseline (cross-sectional)

Study Arms (1)

Healthy

Healthy Volunteers

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Community members and students from the University of Pittsburgh.

You may qualify if:

• For Study A, community members will be invited to participate if they are aged 18 to 70.
• For Study B, University at Pittsburgh students will be invited to participate if they are aged 18 and over.

Sponsors & Collaborators

• National Cancer Institute (NCI): lead

Related Publications (2)

• Lockwood P, Jordan CH, Kunda Z. Motivation by positive or negative role models: regulatory focus determines who will best inspire us. J Pers Soc Psychol. 2002 Oct;83(4):854-64.

  PMID: 12374440 BACKGROUND

• Waters EA, Weinstein ND, Colditz GA, Emmons KM. Aversion to side effects in preventive medical treatment decisions. Br J Health Psychol. 2007 Sep;12(Pt 3):383-401. doi: 10.1348/135910706X115209.

  PMID: 17640453 BACKGROUND

MeSH Terms

Conditions

Neoplasms

Study Officials

• William M Klein

  National Cancer Institute (NCI)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 17, 2016
• First Posted: August 22, 2016
• Study Start: June 5, 2019
• Primary Completion: June 17, 2019
• Study Completion: June 17, 2019
• Last Updated: June 19, 2019

Record last verified: 2019-06