NCT02866513|Completed
Transpulmonary Pressure and Airway Pressure Release Ventilation (APRV).
Incidence of High Levels of Transpulmonary Pressure During the Use of Airway Pressure Release Ventilation.
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Incidence of High Levels of Transpulmonary Pressure During the Use of Airway Pressure Release Ventilation.
Sponsor study identifier
interventional
20
1 country
1
Study Start
February 2016
Actual (reported)Primary Completion
December 2016
Actual (reported)Study Completion
March 2017
Actual (reported)Mechanical ventilation can induce pulmonary lesions called ventilator induced lung injury (VILI). High levels of Transpulmonary pressure is one of the most important mechanism of VILI during the use of mechanical ventilation. The use of bilevel pressure ventilator modes like APRV could generate high levels of transpulmonary pressure. The aim of this study is to evaluate the variations of transpulmonary pressure during the use of APRV by clinicians
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 2017
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 2016
Actual (reported)August 2, 2016
Actual (reported)August 15, 2016
Actual (reported)December 2016
Actual (reported)March 2017
Actual (reported)Transpulmonary pressure
Measurement of transpulmonary pressure needs the measurement of oesophageal pressure with a specific nasogastric tube. This measurement is now available in routine in few mechanical ventilators in intensive care units (eg: AVEA Ventilator. Vyasys HealthCare). Transpulmonary pressure is the difference between airway pressure and oesophageal pressure and it is now easy to obtain and monitor at the bedside with these ventilators. It is also possible to record the value furthermore than 24 hours.
24 hours
Maximal value of transpulmonary pressure
24 hours
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Assistance Publique Hôpitaux de Marseille hôpital de la Timone
Marseille, 13354, France
Urielle DESALBRES
Assistance Publique Hôpitaux de Marseille
20 participants (actual enrollment reported by the registry).
First Submitted
August 2, 2016
First Posted
August 15, 2016
Study Start
February 2016
Actual (reported)Primary Completion
Contact the study team to confirm eligibility.
December 2016
Actual (reported)Study Completion
March 2017
Actual (reported)Last Updated
November 14, 2017
Record last verified: 2016-08
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Source: ClinicalTrials.gov.
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