Biomarkers of Online Gambling Addiction
BLUNDER
1 other identifier
interventional
73
0 countries
N/A
Brief Summary
The purpose of this study is to identify alterations of motivational processes related to decision making in uncertainty condition associated with gambling addiction: by studying the dynamics between brain systems involved in decision making and motivation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Sep 2016
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 20, 2016
CompletedFirst Posted
Study publicly available on registry
August 11, 2016
CompletedStudy Start
First participant enrolled
September 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2019
CompletedAugust 11, 2016
August 1, 2016
2.8 years
July 20, 2016
August 10, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
average activation for each functional neuroimaging examination
day 7 ; day 14
Secondary Outcomes (1)
correlations between various examinations and strength of neuronal response
day 7 ; day 14
Study Arms (3)
validation of EEfRT task
EXPERIMENTAL20 healthy volunteers will be recruted to validate motivation EEfRT task which is adaptated to HR-EEG
biomarkers identification
EXPERIMENTAL20 addict online poker gamblers and 20 non-addict online poker gamblers will be recruted : After standardized questionnaires to define the socio-demographic data, the diagnosis of gambling addiction (Diagnostic and Statistical Manual of Mental Disorder 5th edition DSM-5), screening for comorbidities addictive, the level of anxiety and impulsivity, brain acvtivity will be registred (by randomisation between the 2 tasks) with HR-EEG: during the performance of a task of motivation evaluation laboratory (EEfRT) adaptated for high-resolution electroencephalography AND during a laboratory task that assesses decision making in conditions of uncertainty (IGT) with its version for high-resolution electroencephalography has already been validated in a previous study (Giustiniani et al., 2015).
biomarkers validation
EXPERIMENTAL13 online poker gamblers will be recruted, independently of their dependance profile and they will realize the same task that in precedent arm (quaestionnaires and 2 tasks adaptated to HR-EEG).
Interventions
Eligibility Criteria
You may qualify if:
- right-handed
- stage 1: healthy volunteers (no online poker gamblers and no-addict (excepted tobacco and caffeine))
- stage 2 : 20 addict-online pokers gamblers and 20 non addict online pokers gamblers (according to ICJE criteria)
- stage 3 : 13 online poker gamblers (independently of their dependence level)
You may not qualify if:
- left-handed
- female
- stage 1 and 2: other addictive pathology excepted tobacco and caffeine
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Giustiniani J, Gabriel D, Nicolier M, Monnin J, Haffen E. Neural Correlates of Successful and Unsuccessful Strategical Mechanisms Involved in Uncertain Decision-Making. PLoS One. 2015 Jun 18;10(6):e0130871. doi: 10.1371/journal.pone.0130871. eCollection 2015.
PMID: 26086196BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Julie GIUSTINIANI, MD
University Hospital of Besancon
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SCREENING
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 20, 2016
First Posted
August 11, 2016
Study Start
September 1, 2016
Primary Completion
July 1, 2019
Study Completion
July 1, 2019
Last Updated
August 11, 2016
Record last verified: 2016-08
Data Sharing
- IPD Sharing
- Will not share