NCT02860533

Brief Summary

The iPARR DELTA BP Study is designed to evaluate whether a new smartphone app using the photoplethysmography signal of the inbuilt camera can measure blood pressure (BP) fluctuations with sufficient correlation compared to the goldstandard oscillometric BP measurements. Investigators will recruit patients who are scheduled for a routine treadmill stress test and assess their blood pressure before and right after the test with the smartphone app and the standard BP measurements on the opposite upper extremity. Pronounced BP fluctuations are encountered during vigorous activities. The primary endpoint of the iPARR DELTA BP Study is the correlation of the absolute difference of subsequent measurements between both techniques. If the relative chances of BP fluctuations are sufficiently assessed with this new device, BP fluctuations could be monitored continuously after calibration.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
220

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2016

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 20, 2016

Completed
20 days until next milestone

First Posted

Study publicly available on registry

August 9, 2016

Completed
23 days until next milestone

Study Start

First participant enrolled

September 1, 2016

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2017

Completed
Last Updated

May 7, 2019

Status Verified

May 1, 2019

Enrollment Period

5 months

First QC Date

July 20, 2016

Last Update Submit

May 6, 2019

Conditions

Keywords

Blood pressuresmartphone AppHypertensionStress testingPreventionCardiovascular risk factors

Outcome Measures

Primary Outcomes (1)

  • Absolute difference between conventional blood pressure measurements and the corresponding iPhone blood pressure estimations

    Difference between the delta of two sequential oscillometric measurements and the delta of the two corresponding blood pressure estimates calculated from the PPG signal of an iPhone 4S

    1 day

Secondary Outcomes (1)

  • Number of measurement failures

    1 day

Study Arms (1)

Blood pressure measurement

EXPERIMENTAL

six repetitive blood pressure measurements with iPhone and conventional oscillometric cuff device during stress testing will be performed

Device: cuff deviceDevice: iphone

Interventions

Measurement of blood pressure during stress testing with cuff device

Blood pressure measurement
iphoneDEVICE

Measurement of blood pressure during stress testing with iPhone

Blood pressure measurement

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \- able to give informed consent

You may not qualify if:

  • atrial fibrillation
  • medical reasons why blood pressure measurement is not possible at the upper extremity (Shunt, Lymphedema)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Basel

Basel, Canton of Basel-City, 4031, Switzerland

Location

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Officials

  • Jens Eckstein, MD, PhD

    University Hospital, Basel, Switzerland

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 20, 2016

First Posted

August 9, 2016

Study Start

September 1, 2016

Primary Completion

February 1, 2017

Study Completion

February 1, 2017

Last Updated

May 7, 2019

Record last verified: 2019-05

Data Sharing

IPD Sharing
Will not share

Locations