NCT02858544

Brief Summary

The primary goal of this study is to provide clinicians with a brief, patient self-administer instrument yielding a single composite score that reliably correlates with objective findings on standardized neurocognitive assessment for concussion.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,790

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2013

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 2, 2016

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 8, 2016

Completed
Last Updated

August 8, 2016

Status Verified

August 1, 2016

Enrollment Period

2.6 years

First QC Date

August 2, 2016

Last Update Submit

August 3, 2016

Conditions

Keywords

Mild traumatic brain injury

Outcome Measures

Primary Outcomes (1)

  • Correlation - Concussion Identification Index score with ImPACT test score

    Within 90 days of the accident

Secondary Outcomes (1)

  • Patient-completed one page questionnaire

    Within 90 days of the accident

Study Arms (2)

Group1 - Validation Group

n=890 patients seen and evaluated for possible concussion after a motor vehicle accident. Patients with qualifying scores on the Concussion Identification Index will also complete the ImPACT.

Other: The Concussion Identification IndexOther: ImPACT

Group 2 - Cross Validation Group

n=900 patients seen and evaluated for possible concussion after a motor vehicle accident. Patients with qualifying scores on the Concussion Identification Index will also complete the ImPACT.

Other: The Concussion Identification IndexOther: ImPACT

Interventions

Patient completion of the Concussion Identification Index, a report of crash characteristics, injuries sustained, and post-accident neurological signs and symptoms

Group 2 - Cross Validation GroupGroup1 - Validation Group
ImPACTOTHER

Patient- completed computerized neurocognitive test battery

Group 2 - Cross Validation GroupGroup1 - Validation Group

Eligibility Criteria

Age10 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Cohort 1 - Validation Group: Consecutive patients who presented for care between November 1, 2013 and December 31, 2014 at the MVA Center for Rehabilitation, a public health clinic in Springfield, MA which provides specialized outpatient auto accident treatment and rehabilitation Cohort 2 - Cross Validation Group: Consecutive patients who presented for care between January 1, 2015 and June 30, 2016 at the MVA Center for Rehabilitation, a public health clinic in Springfield, MA

You may qualify if:

  • Patients injured in a motor-vehicle related accident

You may not qualify if:

  • Age younger than 10 years old or older than 60 years of age
  • Patients who presented for initial evaluation of injuries greater than 90 days after MVA occurred
  • Patients who declined to take a computerized neurocognitive test battery
  • Patients who were not fluent in either English or Spanish

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clionsky Neuro Systems, Inc.

Springfield, Massachusetts, 01105, United States

Location

MeSH Terms

Conditions

Brain Injuries, TraumaticBrain ContusionBrain InjuriesBrain Concussion

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesCraniocerebral TraumaTrauma, Nervous SystemWounds and InjuriesContusionsWounds, NonpenetratingHead Injuries, Closed

Study Officials

  • Mitchell I Clionsky, Ph.D

    Clionsky Neuro Systems Inc.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 2, 2016

First Posted

August 8, 2016

Study Start

November 1, 2013

Primary Completion

June 1, 2016

Study Completion

June 1, 2016

Last Updated

August 8, 2016

Record last verified: 2016-08

Data Sharing

IPD Sharing
Will not share

Locations