NCT02852928

Brief Summary

Generation of a common European database and biobank Continous assessment and implementation of guidelines and treatment protocols Establishment of a large observational cohort of chILD patients Determination the value of outcomes used in child Assess treatment variations used, deliver data from defined protocols and linked outcomes

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
44mo left

Started Dec 2013

Longer than P75 for all trials

Geographic Reach
3 countries

3 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress78%
Dec 2013Dec 2029

Study Start

First participant enrolled

December 1, 2013

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

July 29, 2016

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 2, 2016

Completed
12.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2028

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2029

Last Updated

September 21, 2022

Status Verified

September 1, 2022

Enrollment Period

15 years

First QC Date

July 29, 2016

Last Update Submit

September 18, 2022

Conditions

Keywords

ILD; chILD

Outcome Measures

Primary Outcomes (1)

  • Included subjects with specific diagnosis

    Number of recruited subjects

    10 years

Secondary Outcomes (1)

  • Survial

    10 years

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

400 prevalent patients with childhood interstitial lung disease (chILD) in Europe 100 incident chILD cases per year

You may qualify if:

  • all children with suspected or
  • verified diagnosis of ILD or
  • masquerading as ILD and
  • those with rare localized parenchymal lung diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Medizinische Hochschule Hannover

Hanover, Lower Saxony, 30625, Germany

RECRUITING

Hacettepe University, Medical Faculty

Ankara, Sihhiye, 06100, Turkey (Türkiye)

RECRUITING

University of Edinburgh

Edinburgh, EH4 2XU, United Kingdom

RECRUITING

Related Publications (1)

  • Griese M, Seidl E, Hengst M, Reu S, Rock H, Anthony G, Kiper N, Emiralioglu N, Snijders D, Goldbeck L, Leidl R, Ley-Zaporozhan J, Kruger-Stollfuss I, Kammer B, Wesselak T, Eismann C, Schams A, Neuner D, MacLean M, Nicholson AG, Lauren M, Clement A, Epaud R, de Blic J, Ashworth M, Aurora P, Calder A, Wetzke M, Kappler M, Cunningham S, Schwerk N, Bush A; the other chILD-EU collaborators. International management platform for children's interstitial lung disease (chILD-EU). Thorax. 2018 Mar;73(3):231-239. doi: 10.1136/thoraxjnl-2017-210519. Epub 2017 Oct 22.

    PMID: 29056600BACKGROUND

Related Links

MeSH Terms

Conditions

Lung Diseases, InterstitialPulmonary Alveolar ProteinosisPulmonary EosinophiliaPulmonary FibrosisRespiratory Distress Syndrome, Newborn

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract DiseasesHypereosinophilic SyndromeEosinophiliaLeukocyte DisordersHematologic DiseasesHemic and Lymphatic DiseasesFibrosisPathologic ProcessesPathological Conditions, Signs and SymptomsRespiratory Distress SyndromeRespiration DisordersInfant, Premature, DiseasesInfant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Matthias Griese, Prof.

    Klinikum der Universität München, Dr. von Haunersches Kinderspital

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
10 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Prof. Dr. med.

Study Record Dates

First Submitted

July 29, 2016

First Posted

August 2, 2016

Study Start

December 1, 2013

Primary Completion (Estimated)

December 1, 2028

Study Completion (Estimated)

December 1, 2029

Last Updated

September 21, 2022

Record last verified: 2022-09

Data Sharing

IPD Sharing
Will not share

Locations