NCT02852460

Brief Summary

To evaluate the influence of rapid recovery on sleep quality following total hip replacement surgery

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
170

participants targeted

Target at P75+ for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2016

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

July 24, 2016

Completed
9 days until next milestone

First Posted

Study publicly available on registry

August 2, 2016

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2016

Completed
Last Updated

August 2, 2016

Status Verified

July 1, 2016

Enrollment Period

5 months

First QC Date

July 24, 2016

Last Update Submit

July 28, 2016

Conditions

Outcome Measures

Primary Outcomes (6)

  • To evaluate the pain, stiffness and joint function of operated limb by McMaster Universities Osteoarthritis Index(WOMAC)

    To evaluate the function and structure of hip joint from the aspect of pain, stiffness and joint function

    6 months

  • To evaluate the anxiety of patients post-operation by Generalized Anxiety Disorder scale-7 (GAD-7)

    6 months

  • To evaluate the sleep quality of patients post-operation by Pittsburgh Sleep Quality Index (PSQI)

    6 months

  • Insomnia severity index

    6 months

  • To evaluate the health related quality of life of patients post-operation by the 12-items Short Form Health Survey (SF-12)

    6 months

  • To evaluate the pain severity of patients post-operation by Visual Analogue Scale (VAS) Pain Score

    6 months

Secondary Outcomes (13)

  • C Reactive Protein (CRP)

    6 months

  • Erythrocyte Sedimentation Rate (ESR)

    6 months

  • To evaluate the quadriceps strength according to grade division standard published by British Medical Research Council

    6 months

  • To evaluate the swelling of operated limb by measure the thigh girth increment

    6 months

  • To evaluate the operation satisfaction of patients by Visual Analogue Scale (VAS) Satisfaction Score

    6 months

  • +8 more secondary outcomes

Study Arms (2)

Experimental group

EXPERIMENTAL

rapid recovery

Other: rapid recovery

Controlled group

NO INTERVENTION

non-rapid recovery

Interventions

Experimental group

Eligibility Criteria

Age20 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \. Primary unilateral total hip arthroplasty;
  • \. Patients with hip osteoarthritis,rheumatoid arthritis or femoral head necrosis;
  • \. Able and willing to provide signed informed consent.

You may not qualify if:

  • \. Simultaneously bilateral total hip arthroplasty or revision case;
  • \. Surgical History of the hip joint;
  • \. Hip joint cavity paracentesis in recent 3 months;
  • \. Stiffness with hip;
  • \. Blood coagulation disorders;
  • \. History of deep venous thrombosis;
  • \. Concomitant medical problems such as uncontrolled hypertension, severe cardiovascular disorder, chronic obstructive pulmonary disease, liver or renal failure
  • \. Allergic to NSAIDs, opioid analgesics, zolpidem
  • \. Sleep apnea, Parkinson disease, dementia, depression
  • \. Use of sedatives or hypnotics
  • \. Unable to comply with polysomnographic measurement

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Southwest Hospital

Chongqing, Chongqing Municipality, 400038, China

RECRUITING

MeSH Terms

Conditions

Sleep Initiation and Maintenance Disorders

Condition Hierarchy (Ancestors)

Sleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

July 24, 2016

First Posted

August 2, 2016

Study Start

April 1, 2016

Primary Completion

September 1, 2016

Last Updated

August 2, 2016

Record last verified: 2016-07

Locations