NCT02842047

Brief Summary

Caregivers of persons with cancer may face many challenges as they support and care for a person receiving treatment. Sometimes having to help make treatment decisions for a patient can cause distress for caregivers. The purpose of this study is to evaluate 2 different electronic approaches to providing support for a caregiver. One group will have access to an on-line program with videos, providing education on decision making strategies for caregivers of patients with cancer, to watch and a daily meditation application and the other group will have access to the daily meditation application. Investigators will randomly assign participants to each group.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2016

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

July 20, 2016

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 22, 2016

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 9, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 9, 2018

Completed
Last Updated

April 4, 2019

Status Verified

April 1, 2019

Enrollment Period

1.7 years

First QC Date

July 20, 2016

Last Update Submit

April 2, 2019

Conditions

Keywords

caregiverend of life

Outcome Measures

Primary Outcomes (2)

  • Repeated Measures ANCOVA Model (F-Statistic)

    Estimation of effect of the intervention

    At 10 months

  • Repeated Measures ANCOVA Model (F-Statistic)

    Estimation of effect of the intervention

    At 1 month

Secondary Outcomes (6)

  • Change in National Comprehensive Cancer Network (NCNN) Distress Thermometer Score

    From baseline to up to 10 months

  • Change in Degner's Decisional Control Scale

    From baseline to up to 10 months

  • Change in End of Life Value

    From baseline to up to 10 months

  • Change in PROMIS-29 Scale

    From baseline to up to 10 months

  • Change in O'Connor's Decisional Regret Scale

    From baseline to up to 10 months

  • +1 more secondary outcomes

Study Arms (2)

End of Life Care with Meditation

EXPERIMENTAL

The intervention has two content components: end of life planning education (using end of life planning videos) and strategies and kindness based meditation (using the Stop, Breathe \& Think™ app). The activities comprising these components work together to improve both analytic neural processing (e.g. improving knowledge about goal setting and EOL planning, learning self-monitoring of EOL values and goals of care, and self-regulation skills of monitoring symptoms of distress and anxiety) and emotional neural processing (e.g. teaching participants to experience the moment non-judgmentally and directing thoughts to think positive thoughts and feel positive feelings like kindness and compassion.

Behavioral: Stop, Breathe & Think™Behavioral: End of Life Planning Videos

Meditation Only

ACTIVE COMPARATOR

This arm has the single content component of kindness based meditation delivered by using the Stop, Breathe \& Think™ application. This group will also be instructed to view 3 caregiver wellness videos.

Behavioral: Stop, Breathe & Think™Behavioral: Caregiver wellness videos

Interventions

online daily meditations delivered using smart phone or other computer based application

Also known as: meditation app
End of Life Care with MeditationMeditation Only

Three videos, each 10 minutes in length which will be viewed over the study period. The videos will walk participants though key aspects of end of life planning.

Also known as: online videos
End of Life Care with Meditation

Three videos, each 10 minutes in length which will be viewed over the study period. The videos will walk participants though general caregiver wellness.

Meditation Only

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • caregivers of patients who have been diagnosed with Stage IV gastrointestinal (GI) cancer
  • coming with the patient at the Seidman Comprehensive Cancer Center at University Hospitals Case Medical Center (UHCMC)
  • have access to the internet and a computer, tablet, or smart phone, and
  • speak and comprehend English.

You may not qualify if:

  • currently practicing mindfulness-based interventions (yoga, meditation, deep breathing)
  • require psychotherapy within the last three months
  • have a history of dementia, major neurological illness
  • pregnant
  • history of a medical condition or procedure that is contraindicated for functional magnetic resonance imaging (fMRI) scanning (i.e. cardiac pacemaker, sternal wires, or metal implants); and
  • claustrophobia requiring anxiolytics or sedation; or
  • expect to relocate from Northeast, Ohio within 2 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center

Cleveland, Ohio, 44106, United States

Location

Related Publications (1)

  • Moore SM, Musil CM, Alder ML, Pignatiello G, Higgins P, Webel A, Wright KD. Building a Research Data Repository for Chronic Condition Self-Management Using Harmonized Data. Nurs Res. 2020 Jul/Aug;69(4):254-263. doi: 10.1097/NNR.0000000000000435.

MeSH Terms

Conditions

Gastrointestinal NeoplasmsDeath

Condition Hierarchy (Ancestors)

Digestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Sara Douglas, PhD, RN

    Case Comprehensive Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 20, 2016

First Posted

July 22, 2016

Study Start

July 1, 2016

Primary Completion

March 9, 2018

Study Completion

March 9, 2018

Last Updated

April 4, 2019

Record last verified: 2019-04

Locations