Survival After Surgical Treatment of Axis Fractures in Elderly
1 other identifier
observational
6,231
0 countries
N/A
Brief Summary
Fractures of the second cervical vertebra (C2) are the most common spinal fracture among the elderly. Non-surgical treatment comprises of cervical collar treatment for 12 weeks, while surgical treatment for elderly could mean posterior fixation C1-C2 without collar treatment or anterior screw osteosynthesis C2 with 6 weeks of collar treatment. A meta-analysis of retrospective studies has recently found an improved survival with surgical treatment. This national registry study is designed to estimate the survival of non-surgical and surgical treatment in a population-based cohort.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2015
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2015
CompletedFirst Submitted
Initial submission to the registry
July 18, 2016
CompletedFirst Posted
Study publicly available on registry
July 20, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2016
CompletedMay 19, 2017
May 1, 2017
1.2 years
July 18, 2016
May 18, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Survival
Survival as registered in Swedish National Cause of Death Registry
Censored observational time (20 years)
Study Arms (2)
Surgical treatment
Patients ≥70 years with C2 fracture coded in patient registry (ICD-10: S12.1) treated with surgical fracture stabilisation
Non-surgical treatment
Patients ≥70 years with C2 fracture coded in patient registry (ICD-10: S12.1) treated non-surgically
Interventions
Cervical collar immobilisation for 12 weeks.
Stabilisation of C2-fracture by posterior fusion C1-C2, posterior fusion C2-C3, anterior fusion C2-C3 (no postoperative collar) or anterior screw osteosynthesis C2 (postoperative collar for 6 weeks).
Eligibility Criteria
National patient registry extract with patients suffering from C2 fracture
You may qualify if:
- C2-fracture
- Age ≥70 years
You may not qualify if:
- no C2-fracture
- Age \<70 years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Robinson Y, Robinson AL, Olerud C. Systematic review on surgical and nonsurgical treatment of type II odontoid fractures in the elderly. Biomed Res Int. 2014;2014:231948. doi: 10.1155/2014/231948. Epub 2014 Feb 10.
PMID: 24683543BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 20 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 18, 2016
First Posted
July 20, 2016
Study Start
October 1, 2015
Primary Completion
December 1, 2016
Study Completion
December 1, 2016
Last Updated
May 19, 2017
Record last verified: 2017-05
Data Sharing
- IPD Sharing
- Will not share