NCT02836808

Brief Summary

Abstract: Empowerment interventions for chronic diseases are an evolving process. No agreement exists regarding the necessary components and methodologies to be applied. Systematic reviews have assessed the effect of self-management interventions. Improvements in illness beliefs, adherence to drug therapy and glucose monitoring have been reported. In the long term, no major changes have been achieved in weight, physical activity, smoking status, and depression scores. There is a need for additional studies. The Center for Comprehensive Care of Patients with Diabetes (CAIPaDi) program is an intervention designed to provide education and empowerment techniques (using simple low-cost interactive tools) over a short period of time followed by at-distance support using internet or cell phone technology. The target population consists of patients with type 2 diabetes, free of chronic complications who are non-smokers. The intervention is composed of four monthly visits followed by a continuous at-distance support system. At each visit, patients stay for six hours in the center. Information is presented in group sessions. Empowerment techniques are applied during individual exchanges with the team or during facilitated group sessions. In summary, empowerment programs are an unmet need in many healthcare services.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,200

participants targeted

Target at P75+ for not_applicable type-2-diabetes

Timeline
33mo left

Started Oct 2013

Longer than P75 for not_applicable type-2-diabetes

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress83%
Oct 2013Dec 2028

Study Start

First participant enrolled

October 31, 2013

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

April 8, 2016

Completed
3 months until next milestone

First Posted

Study publicly available on registry

July 19, 2016

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 9, 2018

Completed
10.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2028

Expected
Last Updated

March 6, 2018

Status Verified

July 1, 2016

Enrollment Period

4.3 years

First QC Date

April 8, 2016

Last Update Submit

March 2, 2018

Conditions

Keywords

Multidisciplinary interventionsLong term controlEmpowerment

Outcome Measures

Primary Outcomes (1)

  • Diabetes control after 4 visits in a structured multidisciplinary program for patients with diabetes

    HbA1c is measured in percentage (%). HbA1c will be compared from the first visit with the fourth visit.

    3 months

Secondary Outcomes (17)

  • Diabetes control after 1 year in a structured multidisciplinary program for patients with diabetes

    1 year

  • Metabolic parameters are lipid profile after 1 year in a structured multidisciplinary program for patients with diabetes

    1 year

  • Renal function after 1 year in a structured multidisciplinary program for patients with diabetes

    1 year

  • Self-care by SDSCA questionnaire after 1 year in a structured multidisciplinary program for patients with diabetes

    1 year

  • Diabetic complications are eye, renal and foot evaluations after 1 year in a structured multidisciplinary program for patients with diabetes

    1 year

  • +12 more secondary outcomes

Other Outcomes (11)

  • Glucose control of the cases attended at the Center compared with those of patients with similar characteristics attended in the "Internal Medicine" service of the INCMNSZ.

    2 years

  • Lipid parameters of the cases attended at the Center compared with those of patients with similar characteristics attended in the "Internal Medicine" service of the INCMNSZ.

    2 years

  • Renal function evaluation of the cases attended at the Center compared with those of patients with similar characteristics attended in the "Internal Medicine" service of the INCMNSZ.

    2 years

  • +8 more other outcomes

Study Arms (2)

Control

NO INTERVENTION

Patients attended with the standard model of care for diabetes, as out-patients in the Internal Medicine area

CAIPaDi

EXPERIMENTAL

Patients attended in the Center of Comprehensive Care for the Patient with Diabetes, where they receive attention from 9 specialists in 1 day

Behavioral: CAIPaDi

Interventions

CAIPaDiBEHAVIORAL

Patients are attended in 1 day by 9 specialists (endocrinologist, diabetes educators, nutritionist, psychologist, dentists, psychiatrist, physical activity specialist, foot care and ophthalmologist). They are attended in 4 monthly visits. After the initial phase, patients come back to the Center at 1 and 2 years for evaluation and reinforcement.

CAIPaDi

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • being over 18 and under 70 years old
  • having diagnosis of type 2 diabetes in the five previous years,
  • having family support
  • free of disabling diabetes complications

You may not qualify if:

  • advanced complications of diabetes, such as ischemic heart disease, heart failure NYHA III-IV, KDOQI ≥3 renal failure, amputations, cerebral vascular disease, gastroparesis and muscular atrophy .
  • type 1 diabetes mellitus, gestational diabetes or some variant of diabetes related to genetic syndromes, hyperlabile diabetes
  • co-morbidities that limit their life expectancy such as malignant tumors
  • advanced cognitive impairment or serious psychiatric disorders
  • smoking, alcoholism or illegal drug dependence
  • conditions that require surgical treatment in the short run or which prevent moderated activity.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Instituto Nacional de Ciencias Medicas y Nutricion

Mexico City, Mexico City, 14000, Mexico

RECRUITING

Related Publications (8)

  • Villalpando S, Shamah-Levy T, Rojas R, Aguilar-Salinas CA. Trends for type 2 diabetes and other cardiovascular risk factors in Mexico from 1993-2006. Salud Publica Mex. 2010;52 Suppl 1:S72-9. doi: 10.1590/s0036-36342010000700011.

    PMID: 20585732BACKGROUND
  • Aguilar Salinas CA, Gómez Diaz RA, Gomez Perez FJ. Diabetes en Mexico: Principales retos y posibles soluciones. Revista ALAD 2011: 19:146-161

    BACKGROUND
  • Tricco AC, Ivers NM, Grimshaw JM, Moher D, Turner L, Galipeau J, Halperin I, Vachon B, Ramsay T, Manns B, Tonelli M, Shojania K. Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis. Lancet. 2012 Jun 16;379(9833):2252-61. doi: 10.1016/S0140-6736(12)60480-2. Epub 2012 Jun 9.

    PMID: 22683130BACKGROUND
  • Planas LG, Crosby KM, Farmer KC, Harrison DL. Evaluation of a diabetes management program using selected HEDIS measures. J Am Pharm Assoc (2003). 2012;52(6):e130-8. doi: 10.1331/JAPhA.2012.11148.

    PMID: 23224336BACKGROUND
  • Hernandez-Jimenez S, Garcia-Ulloa C, Mehta R, Aguilar-Salinas CA, Kershenobich-Stalnikowitz D. Innovative models for the empowerment of patients with type 2 diabetes: the CAIPaDi program. Recent Pat Endocr Metab Immune Drug Discov. 2014;8(3):202-9. doi: 10.2174/1872214808999141110155515.

    PMID: 25381833BACKGROUND
  • Landa-Anell MV, Del Razo-Olvera FM, Bodnar I, Cordova-Isidro B, Lagunas-Valdepena D, Arias-Marroquin AT, Garcia-Ulloa AC, Melgarejo-Hernandez MA, Hernandez-Jimenez S; Group of Study CAIPaDi. Nutritional diagnoses in people with type 2 diabetes: association with metabolic, anthropometric, and dietary parameters. Front Nutr. 2024 Oct 18;11:1473429. doi: 10.3389/fnut.2024.1473429. eCollection 2024.

  • Garcia-Ulloa AC, Almeda-Valdes P, Cuatecontzi-Xochitiotzi TE, Ramirez-Garcia JA, Diaz-Pineda M, Garnica-Carrillo F, Gonzalez-Duarte A, Narayan KMV, Aguilar-Salinas CA, Hernandez-Jimenez S; CAIPaDi Study Group. Detection of sudomotor alterations evaluated by Sudoscan in patients with recently diagnosed type 2 diabetes. BMJ Open Diabetes Res Care. 2022 Dec;10(6):e003005. doi: 10.1136/bmjdrc-2022-003005.

  • Garcia-Ulloa AC, Lechuga-Fonseca C, Del Razo-Olvera FM, Aguilar-Salinas CA, Galaviz KI, Narayan KMV, Hernandez-Jimenez S; Group of Study CAIPaDi. Clinician prescription of lipid-lowering drugs and achievement of treatment goals in patients with newly diagnosed type 2 diabetes mellitus. BMJ Open Diabetes Res Care. 2021 Feb;9(1):e001891. doi: 10.1136/bmjdrc-2020-001891.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Empowerment

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesSocial BehaviorBehavior

Study Officials

  • Sergio C Hernández, MD

    National Institute of Medical Sciences and Nutrition Salvador Zubirán

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sergio Hernández, MD

CONTACT

Carlos A Aguilar-Salinas, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 8, 2016

First Posted

July 19, 2016

Study Start

October 31, 2013

Primary Completion

February 9, 2018

Study Completion (Estimated)

December 31, 2028

Last Updated

March 6, 2018

Record last verified: 2016-07

Data Sharing

IPD Sharing
Will share

Journal publication. The information to be shared will be metabolic parameters and questionaire results. The data will be available on 2016. Metabolic parameters will be obtained from blood samples and the questionnaires results from those self-applied or applied during praxis.

Shared Documents
STUDY PROTOCOL, ICF, CSR, ANALYTIC CODE
Time Frame
January 2018. The data will be available for 5 years
Access Criteria
Undefined

Locations