NCT02834156

Brief Summary

This protocol is a pilot study on standard care. The main goal is to assess the impact of positioning on lumbar puncture process especially on pain sensitivity in children. It's a prospective, monocentric, randomized, open-label, cross-over study. Inclusion period is one year, and number of inclusions forecasted is about 30. Each patient will have one LP in a seated position and one in a lying position.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 30, 2015

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

July 8, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 15, 2016

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 23, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 23, 2017

Completed
Last Updated

March 12, 2018

Status Verified

March 1, 2018

Enrollment Period

2.2 years

First QC Date

July 8, 2016

Last Update Submit

March 8, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain sensitivity during the lumbar puncture procedure.

    It will be evaluated throw specific pain assessment scales according to patient age

    duration of the procedure

Secondary Outcomes (2)

  • Anxiety during the lumbar puncture procedure on a scale of one to ten

    duration of the procedure

  • Time of the lumbar puncture procedure

    duration of the procedure

Study Arms (2)

LP in a seated position then LP in a lying position

OTHER

Patients will have first a lumbar puncture (LP) in a seated position then a LP in a lying position

Other: LP in a seated position then LP in a lying position

LP in a lying position then LP in a seated position

OTHER

Patients will have first a lumbar puncture (LP) in a lying position then a LP in a seated position

Other: LP in a lying position then LP in a seated position

Interventions

LP in a seated position then LP in a lying position
LP in a lying position then LP in a seated position

Eligibility Criteria

Age2 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Age between 2 and 18 years old
  • Patients requiring at least 2 therapeutic lumbar punctures
  • Patients able to receive analgesic procedure according to 20005 good practices recommendation
  • Presence of one parent during LP procedure
  • Child able to use assessment scales
  • LP realized with a 20 G needle
  • Platelets \> 50000
  • Child with prior clinical examination
  • Affiliated to a health care insurance regimen

You may not qualify if:

  • Seated or lying position impossible
  • Lumbar puncture contraindication
  • Patient or parent opposition to second LP realization in the required position
  • Clotting trouble on LP day not allowing the LP procedure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU de Nice

Nice, 06000, France

Location

MeSH Terms

Conditions

Hematologic Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsHematologic DiseasesHemic and Lymphatic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 8, 2016

First Posted

July 15, 2016

Study Start

June 30, 2015

Primary Completion

August 23, 2017

Study Completion

August 23, 2017

Last Updated

March 12, 2018

Record last verified: 2018-03

Data Sharing

IPD Sharing
Will not share

Locations