NCT02832089

Brief Summary

Oral carvedilol administered in escalating doses in patients with atrial fibrillation among patients with AF with fast ventricular rate.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for phase_3 atrial-fibrillation

Timeline
Completed

Started Dec 2000

Shorter than P25 for phase_3 atrial-fibrillation

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2000

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2002

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2002

Completed
13.8 years until next milestone

First Submitted

Initial submission to the registry

December 28, 2015

Completed
7 months until next milestone

First Posted

Study publicly available on registry

July 14, 2016

Completed
Last Updated

July 14, 2016

Status Verified

July 1, 2016

Enrollment Period

1.2 years

First QC Date

December 28, 2015

Last Update Submit

July 11, 2016

Conditions

Atrial Fibrillation

Keywords

atrial fibrillationrate reduction

Outcome Measures

Primary Outcomes (1)

  • reduction in ventricular rate in AF patients

    reduction in ventricular rate in patients with AF and fast ventricular rate.

    24 hours

Study Arms (1)

active arm

EXPERIMENTAL

single arm study with one group given oral carvedilol.

Drug: oral carvedilol

Interventions

oral carvedilolDRUG

oral carvedilol in escalating doses for reducing ventricular rate in AF patients

Also known as: oral carvedilol in esclating doses
active arm

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • AF with fast ventricular rate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Atrial Fibrillation

Interventions

Carvedilol

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

PropanolaminesAmino AlcoholsAlcoholsOrganic ChemicalsPropanolsAminesCarbazolesIndolesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-RingHeterocyclic CompoundsHeterocyclic Compounds, 3-Ring

Study Design

Study Type
interventional
Phase
phase 3
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
doctor

Study Record Dates

First Submitted

December 28, 2015

First Posted

July 14, 2016

Study Start

December 1, 2000

Primary Completion

March 1, 2002

Study Completion

March 1, 2002

Last Updated

July 14, 2016

Record last verified: 2016-07

Data Sharing

IPD Sharing
Will not share