Investigative Mathematical Modeling of Hospital Transmission of Hepatitis C
IMMHoTHep
ANRS 12320 IMMHoTHep : Investigative Mathematical Modeling of Hospital Transmission of Hepatitis C
1 other identifier
observational
550
1 country
1
Brief Summary
This project is a prospective observational cohort study to quantify the risk of acquiring Hepatitis C virus (HCV) infection for patients and healthcare workers in Ain Shams University Teaching Hospital, Cairo, Egypt through: 1) identifying typical patient trajectories within the hospital; and 2) assessing the ward-specific risk based on the type and number of procedures performed and the prevalence of HCV viremia in patients within each ward.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 30, 2016
CompletedFirst Posted
Study publicly available on registry
July 11, 2016
CompletedStudy Start
First participant enrolled
February 21, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2018
CompletedApril 10, 2017
April 1, 2017
1.1 years
June 30, 2016
April 7, 2017
Conditions
Outcome Measures
Primary Outcomes (2)
Per-day risk of HCV acquisition for a hospitalized patient
Per-day risk of HCV acquisition for a hospitalized patient
1 day
Per-week risk of HCV acquisition for a healthcare worker through occupational blood exposure
Per-week risk of HCV acquisition for a healthcare worker through occupational blood exposure
1 week
Secondary Outcomes (1)
Estimation of the number of HCV acquisitions among patients and HCWs prevented over a 1-year period following the implementation of various control strategies, using a mathematical modeling approach
1 year
Study Arms (2)
Patients
500 patients who are going to be hospitalized for at least 24 hours at Ain Shams University Teaching Hospital in the following departments: surgery, internal medicine, gynecology/obstetrics and toxicology.
Healthcare workers
50 healthcare workers working at Ain Shams University Teaching Hospital in the following departments: surgery, internal medicine, gynecology/obstetrics and toxicology.
Eligibility Criteria
500 patients staying at least 24 hours in one of the following departments of the Ain Shams University Teaching Hospital: surgery, internal medicine, gynecology/obstetrics and toxicology. 50 healthcare workers working in one of departments cited above.
You may qualify if:
- Aged 21 years or older
- Staying in the hospital more than 24 hours
- Provided a written informed consent to participate
- Aged 21 or older
- Provided a written informed consent to participate
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- ANRS, Emerging Infectious Diseaseslead
- Conservatoire national des Arts et Métierscollaborator
- Ain Shams Universitycollaborator
- Institut Pasteurcollaborator
Study Sites (1)
Ain Shams University Teaching Hospital
Cairo, Egypt
Biospecimen
Blood sample (5mL)
Study Officials
- PRINCIPAL INVESTIGATOR
Laura Temime, Professor
Conservatoire national des Arts et Métiers
- PRINCIPAL INVESTIGATOR
Wagida Anwar, Professor
Ain Shams University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 2 Weeks
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 30, 2016
First Posted
July 11, 2016
Study Start
February 21, 2017
Primary Completion
April 1, 2018
Study Completion
April 1, 2018
Last Updated
April 10, 2017
Record last verified: 2017-04