Use of Compressed Sensing in Breast MRI

NCT02826369 | Completed

• 1 other identifier: 2015-A00581-48
• Study Type: interventional
• Target: 13
• Locations: 1 country
• Sites: 1

Brief Summary

Breast MRI is increasingly important in breast screening imaging. It is currently based on dynamic sequences after contrast injection whose temporal resolution must be less than 90 seconds with dynamic acquisitions at different times. These curves profiles are designed to differentiate benign from malignant lesions. Recently, Mann et al, (2014) showed that increasing the temporal resolution of dynamic acquisitions; lesion enhancement curves over time were more accurate than the curves usually performed. It seems necessary to work on sequences having better temporal resolution without compromising however spatial resolution.

Conditions

Breast Cancer

Keywords

Algorithms; Image Processing, Computer-Assisted/methods*; Magnetic Resonance Imaging/methods*; Data Compression; Breast Neoplasms

Outcome Measures

Primary Outcomes (1)

• Agreement between compressed sensing and standard image acquisition

  Agreement between compressed sensing and standard image acquisition is defined by percentage of lesions detected by both modes of acquisitions

  1 day

Secondary Outcomes (2)

• Analysis of dammage contours

  1 day

• Image quality in compressed sensing acquisition

  1 day

Study Arms (1)

3.0 Tesla in Magnetic Resonance Imaging

EXPERIMENTAL

Other: 3.0 Tesla in Magnetic Resonance Imaging

Interventions

3.0 Tesla in Magnetic Resonance Imaging OTHER

Eligible patient will have a standard MRI. The images taken before 4min30 and after 6min after to the injection of gadolimium contrast medium will be carried out with the standard image acquisition. The images taken between 4min30 and 6min after the injection of gadolimium contrast medium will be carried out with the compressed sensing image acquisition.

3.0 Tesla in Magnetic Resonance Imaging

Eligibility Criteria

• Age: Up to 18 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Patient to benefit a MRI in the assessment for a breast carcinoma
• Age \>18 years old
• Assessment on 3.0 Tesla in Magnetic Resonance Imaging
• ECOG performance status ≤ 3
• Ability to provide an informed written consent form

You may not qualify if:

• Age \< 18 years old
• Claustrophobia
• Contraindication to the injection of gadolinium contrast medium
• Contraindication to MRI
• Persons deprived of liberty or under supervision

Sponsors & Collaborators

• Institut de Cancérologie de Lorraine: lead

Study Sites (1)

Institut de Cancérologie de Lorraine

Vandœuvre-lès-Nancy, 54500, France

Location

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Magnetic Resonance Spectroscopy

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Spectrum Analysis; Chemistry Techniques, Analytical; Investigative Techniques

Study Officials

• OLDRINI Guillaume, MD

  Institut de Cancérologie de Lorraine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 5, 2016
• First Posted: July 11, 2016
• Study Start: March 29, 2016
• Primary Completion: April 12, 2016
• Study Completion: April 12, 2016
• Last Updated: August 8, 2018

Record last verified: 2018-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)